Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

4091-4100 of 6380 results

Catalogue Number:

HPAB-0028-YC

Category:

A

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Human Anti-MMP9 Recombinant Antibody (clone G03-VH-GL-V1/ G06-VL-GL1)

Target: MMP9
Target Alias Names: GELB, CLG4B, MMP-9, MANDP2
Species Reactivity: Human
Application: Other
Type: Primary Recombinant
Isotype/Mimetic: Human IgG4
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0200-FY

Category:

A

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Human Anti-MMP9 Recombinant Antibody (clone M0279-A03)

Target: MMP9
Target Alias Names: Matrix Metallopeptidase 9, Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), EC 3.4.24.35, CLG4B, MMP-9, GELB, Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), Matrix Metalloproteinase-9
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-1320-FY

Category:

A

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Human Anti-MMP9 Recombinant Antibody (HPAB-1320-FY)

Target: MMP9
Target Alias Names: Matrix Metallopeptidase 9, Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), EC 3.4.24.35, CLG4B, MMP-9, GELB, Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), Matrix Metalloproteinase-9
Species Reactivity: Human, Mouse
Application: Other
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0633-CN

Category:

A

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Human Anti-MMP9/ MMP2 Recombinant Antibody (HPAB-0633-CN)

Target: MMP9/ MMP2
Target Alias Names: Matrix Metallopeptidase 9, Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), EC 3.4.24.35, CLG4B, MMP9, GELB, Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), Matrix Metalloproteinase-9
Species Reactivity: Mouse
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

PABC-109

Category:

A

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Human Anti-MOG Recombinant Antibody (clone 8-18C5)

Target: MOG
Target Alias Names: MOG, myelin oligodendrocyte glycoprotein, myelin-oligodendrocyte glycoprotein, dystonia 2, torsion (autosomal recessive)
Species Reactivity: Rat
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: Chimeric (mouse/human) IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0777-YJ

Category:

A

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Human Anti-Mouse KDR Recombinant Antibody (VC16)

Target: KDR
Target Alias Names: orv, Flk1, Ly73, Flk-1, Krd-1, VEGFR2, VEGFR-2, sVEGFR-2, 6130401C07, vascular endothelial growth factor receptor 2, fetal liver kinase-1, kinase insert domain receptor (a type III receptor tyrosine kinase), protein-tyrosine kinase receptor Flk-1, soluble VEGFR2, tyrosine kinase growth factor receptor
Species Reactivity: Mouse
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: Chimeric (rabbit/human) IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

PABJ-0148

Category:

A

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Human Anti-MPIG6B Recombinant Antibody (clone AB174)

Target: MPIG6B
Target Alias Names: G6b, NG31, G6b-B, THAMY, C6orf25
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-S0096-YC

Category:

A

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Human Anti-MPL Recombinant Antibody (clone 10D10)

Target: MPL
Target Alias Names: MPL Proto-Oncogene, Thrombopoietin Receptor, Myeloproliferative Leukemia Virus Oncogene, Myeloproliferative Leukemia Protein, Proto-Oncogene C-Mpl, TPO-R, TPOR, Thrombopoietin Receptor
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-S0095-YC

Category:

A

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Human Anti-MPL Recombinant Antibody (clone 10F6)

Target: MPL
Target Alias Names: MPL Proto-Oncogene, Thrombopoietin Receptor, Myeloproliferative Leukemia Virus Oncogene, Myeloproliferative Leukemia Protein, Proto-Oncogene C-Mpl, TPO-R, TPOR, Thrombopoietin Receptor
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-S0097-YC

Category:

A

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Human Anti-MPL Recombinant Antibody (clone 5E5)

Target: MPL
Target Alias Names: MPL Proto-Oncogene, Thrombopoietin Receptor, Myeloproliferative Leukemia Virus Oncogene, Myeloproliferative Leukemia Protein, Proto-Oncogene C-Mpl, TPO-R, TPOR, Thrombopoietin Receptor
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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