Description
The c-mpl agonist antibody is shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells.
Target
MPL
Target Alias Names
MPL Proto-Oncogene, Thrombopoietin Receptor, Myeloproliferative Leukemia Virus Oncogene, Myeloproliferative Leukemia Protein, Proto-Oncogene C-Mpl, TPO-R, TPOR, Thrombopoietin Receptor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression