Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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3911-3920 of 5093 results

Catalogue Number:

AP1506

Category:

Phospho-PKC alpha-T410+PKC delta-T410 Rabbit mAb

Target:	PRKCZ
Target Alias Names:	AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha, PKC-alpha, Phospho-PKC alpha-T410+PKC delta-T410
Species Reactivity:	Human
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1375

Category:

Phospho-PKC alpha-T638 + PKC beta II-T641 Rabbit mAb

Target:	PRKCA/PRKCB
Target Alias Names:	PKC-beta, PKCB, PRKCB1, PRKCB2, Phospho-PKC alpha-T638 + PKC beta II-T641
Species Reactivity:	Human
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1045

Category:

Phospho-PKC alpha-T638 Rabbit mAb

Reference available

Target:	PRKCA
Target Alias Names:	AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha, PKC-alpha, Phospho-PKC alpha-T638
Species Reactivity:	Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1376

Category:

Phospho-PKC alpha-T638 Rabbit mAb

Target:	PRKCA
Target Alias Names:	AAG6, PKCA, PRKACA, PKCI+/-, PKCalpha, PKC-alpha, Phospho-PKC alpha-T638
Species Reactivity:	Human
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1149

Category:

Phospho-PKC zeta-T560 Rabbit mAb

Target:	PRKCZ
Target Alias Names:	PKC2, PKC-ZETA, Phospho-PKC zeta-T560
Species Reactivity:	Human, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

75148

Category:

Phospho-PKD/PKCμ (Ser910) (E7M8C) Rabbit mAb

Target:	PKD1/PKCmu (Ser910) phosphate
Target Alias Name:	PRKD1
Species Reactivity:	Human, Mouse
Application:	Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1134

Category:

Phospho-PKR/EIF2AK2-T446 Rabbit mAb

References available

Target:	EIF2AK2
Target Alias Names:	PKR, PRKR, DYT33, LEUDEN, EIF2AK1, PPP1R83, Phospho-PKR/EIF2AK2-T446
Species Reactivity:	Human
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1496

Category:

Phospho-PLC gamma 1 (PLCG1)-S1248 Rabbit mAb

Target:	PLCG1
Target Alias Names:	PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1
Species Reactivity:	Human, Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1340

Category:

Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb

Reference available

Target:	PLCG1
Target Alias Names:	PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1, Phospho-PLC gamma 1 (PLCG1)-Y783
Species Reactivity:	Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1574

Category:

Phospho-PLC gamma 2 (PLCG2)-Y1217 Rabbit mAb

Target:	PLCG2
Target Alias Names:	FCAS3, APLAID, PLC-IV, PLC-gamma-2
Species Reactivity:	Human
Applications:	Immunofluorescence, Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Viewing 3911-3920 of 5093 results

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