Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

301-310 of 5093 results

Catalogue Number:

A24358

Category:

ABflo? 488 Rabbit anti-Human Siglec-8 mAb

Target:	SIGLEC8
Target Alias Names:	SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L, sialic acid-binding Ig-like lectin 8
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgM
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A24572

Category:

ABflo? 488 Rabbit anti-Human T-bet/Tbx21 mAb

Target:	TBX21
Target Alias Names:	TBX21, T-PET, T-bet, TBET, TBLYM, T-box 21
Species Reactivity:	Human
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A22158

Category:

ABflo? 488 Rabbit anti-Human TIM-3/HAVCR2 mAb

Target:	HAVCR2
Target Alias Names:	TIM3, CD366, KIM-3, SPTCL, TIMD3, Tim-3, TIMD-3, HAVcr-2
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A26872

Category:

ABflo? 488 Rabbit anti-Human TREM1 mAb

Target:	TREM1
Target Alias Names:	CD354, TREM-1
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A22577

Category:

ABflo? 488 Rabbit anti-Human TROP-2 mAb

Target:	TACSTD2
Target Alias Names:	EGP1, GP50, M1S1, EGP-1, TROP2, GA7331, GA733-1
Species Reactivity:	Human
Applications:	Flow Cytometry, Immunofluorescence
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A24360

Category:

ABflo? 488 Rabbit anti-Human TROP-2 mAb

Target:	TACSTD2
Target Alias Names:	TACSTD2, EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2, tumor-associated calcium signal transducer 2
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgM
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A25161

Category:

ABflo? 488 Rabbit anti-Human/Monkey CD127/IL-7Rα mAb

Target:	IL7R
Target Alias Names:	ILRA, CD127, IL7RA, CDW127, IMD104, sIL-7R, lnc-IL7R, IL7Ralpha, IL-7Ralpha, IL-7R-alpha, CD127/IL7R
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A27215

Category:

ABflo? 488 Rabbit anti-Human/Monkey CD18 mAb

Target:	ITGB2
Target Alias Names:	LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A23008

Category:

ABflo? 488 Rabbit anti-Human/Monkey CD19 mAb

Target:	CD19
Target Alias Name:	CD19
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

A26933

Category:

ABflo? 488 Rabbit anti-Human/Monkey CD56/NCAM1 mAb

Target:	NCAM1
Target Alias Names:	CD56, NCAM, MSK39
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	ABflo? 488. Ex:491nm. Em:516nm.
Formulation:	PBS with 0.09% Sodium azide, 0.2% BSA, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Viewing 301-310 of 5093 results

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