Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

2541-2550 of 4090 results

Catalogue Number:

PTX18518-100

Category:

CD274 / PD-L1 / B7-H1 Monoclonal Monoclonal Antibody 2C11

Target:	CD274
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX18519-100

Category:

CD274 / PD-L1 / B7-H1 Monoclonal Monoclonal Antibody 5H8

Target:	CD274
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2b
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX18527-100

Category:

CD38 Monoclonal Monoclonal Antibody 9H2

Target:	CD38
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1
Host Species:	Other
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1154

Category:

CDP571 Biosimilar – Anti-TNFSF2/ TNF alpha/ TNFA mAb – Research Grade

Target:	TNFSF2/ TNF alpha/ TNFA
Target Alias Name:	CDP571/B3 (dsFv) -PE38/LMB-9 BAY 103356/BAY W 3356/CDP571/TNFSF2/ TNF alpha/ TNFA/anti-TNFSF2/ TNF alpha/ TNFA
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1056

Category:

Cedelizumab Biosimilar – Anti-CD4 mAb – Research Grade

Target:	CD4
Target Alias Name:	Cedelizumab/ORTHOCLONE OKT4 A/CD4/anti-CD4
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1524

Category:

Cemiplimab Biosimilar – Anti-PDCD1/ PD1/ CD279 mAb – Research Grade

Target:	PDCD1/ PD1/ CD279
Target Alias Name:	Cemiplimab/REGN-2810/SAR-439684/cemiplimab-rwlc/PDCD1/ PD1/ CD279/anti-PDCD1/ PD1/ CD279
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1557

Category:

Cendakimab Biosimilar – Anti-IL13 mAb – Research Grade

Target:	IL13
Target Alias Name:	Cendakimab /13C5.5/ABT-308/RPC-4046/IL13/anti-IL13
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2112

Category:

Cepeprubart Biosimilar – Anti-Selectin P ligand mAb – Research Grade

Target:	Selectin P ligand
Species Reactivity:	Human
Application:	ELISA
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1387

Category:

Cergutuzumab Biosimilar – Anti-CEACAM5/ CEA/ CD66e mAb – Research Grade

Target:	CEACAM5/ CEA/ CD66e
Target Alias Name:	Cergutuzumab/CEA-IL-2v/RG7813/RO-6895882/CEACAM5/ CEA/ CD66e/anti-CEACAM5/ CEA/ CD66e
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IG-Gamma1 -[IL2 (interleukin 2/ IL-2) 21-153/ engineered]1_kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1024

Category:

Certolizumab Biosimilar – Anti-TNF-Alpha mAb – Research Grade

Target:	TNF-Alpha
Target Alias Name:	Certolizumab/Certolizumab/TNF-Alpha/anti-TNF-Alpha
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	Fab'G1Kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 2541-2550 of 4090 results

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