Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

2531-2540 of 4090 results

Catalogue Number:

PX-TA1278

Category:

Caplacizumab Biosimilar – Anti-VWF A1 domain mAb – Research Grade

Target:	VWF A1 domain
Target Alias Name:	Caplacizumab/ALX-0081/PMP12A2h1-linker AAA-PMP12A2h1/caplacizumab-yhdp/VWF A1 domain/anti-VWF A1 domain
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	VH-VH
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1078

Category:

Capromab Biosimilar – Anti-FOLH2 mAb – Research Grade

Target:	FOLH2
Target Alias Name:	Capromab/7E11-C5.3 radiolabelled/Indium In1111 ProstaScint-/capromab pendetide/FOLH2/anti-FOLH2
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1252

Category:

Carlumab Biosimilar – Anti-CCL2/ MCP-1/ MCAF/ SCYA2 mAb – Research Grade

Target:	CCL2/ MCP-1/ MCAF/ SCYA2
Target Alias Name:	Carlumab/CNTO 888/CCL2/ MCP-1/ MCAF/ SCYA2/anti-CCL2/ MCP-1/ MCAF/ SCYA2
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1421

Category:

Carotuximab Biosimilar – Anti-ENG mAb – Research Grade

Target:	ENG
Target Alias Name:	Carotuximab/TRC-105/c-SN6j/ENG/anti-ENG
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2053

Category:

Casdozokitug Biosimilar – Anti-p28 mAb – Research Grade

Target:	p28
Target Alias Name:	anti-p28/ Interleukin-27 subunit alpha/ IL-27 subunit alpha/ IL27A/ IL27/ IL-27-A/ Interleukin-30/ IL30/ IL27-A
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1108

Category:

cBR96 Biosimilar – Anti-Lewis Y mAb – Research Grade

Target:	Lewis Y
Target Alias Name:	cBR96/cBR96/huAnti-B4/humanized B1-8/humanized D1.3/humanized DX48/humanized K20/humanized-HCMV16/humanized-HCMV37//Lewis Y/anti-Lewis Y
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa/
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1929

Category:

CC-90002 Biosimilar – Anti-Leukocyte surface antigen CD47 mAb – Research Grade

Target:	Leukocyte surface antigen CD47
Target Alias Name:	anti-Leukocyte surface antigen CD47/ CD47/ Antigenic surface determinant protein OA3/ IAP/ Integrin-associated protein/ Protein MER6/ MER6/
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1097

Category:

Cc49 Biosimilar – Anti-TAG-72 mAb – Research Grade

Target:	TAG-72
Target Alias Name:	Cc49/CC49/TAG-72/anti-TAG-72
Species Reactivity:	Human
Type:	Primary Recombinant
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX18504-100

Category:

CD14 Monoclonal Monoclonal Antibody 6B11

Target:	CD14
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1
Host Species:	Other
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX18517-100

Category:

CD274 / PD-L1 / B7-H1 Monoclonal Monoclonal Antibody 11F5

Target:	CD274
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 2531-2540 of 4090 results

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