Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

9701-9710 of 84783 results

Catalogue Number:

HF636046

Category:

A

Anti-Human Complement C3 Reference Antibody (NGM621, RUO)

Target: Complement C3
Target Alias Names: C3, ASP, Complement C3, C3adesArg, C3bc, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF831107

Category:

A

Anti-Human Complement C4 Recombinant Antibody (SAA0109)

Target: LYPD3
Target Alias Names: C4.4A, Matrigel-induced gene C4 protein, GPI-anchored metastasis-associated protein C4.4A homolog, MIG-C4, LYPD3, Ly6/PLAUR domain-containing protein 3
Species Reactivity: Human
Application: Flow Cytometry
Type: Primary Recombinant
Isotypes/Mimetics: IgG1, lambda
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF831016

Category:

A

Anti-Human Complement C4 Reference Antibody (Lupartumab, RUO)

Target: LYPD3
Target Alias Names: C4.4A, Matrigel-induced gene C4 protein, GPI-anchored metastasis-associated protein C4.4A homolog, MIG-C4, LYPD3, Ly6/PLAUR domain-containing protein 3
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687096

Category:

A

Anti-Human Complement C5 & ALB Bispecific Reference Antibody (Gefurulimab, RUO)

Target: C5 & ALB
Target Alias Names: CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5, ALB, Albumin
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: VH-VH'
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687196

Category:

A

Anti-Human Complement C5 Reference Antibody (Ascuprubart, RUO)

Target: C5/ComplementC5
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG H-gamma2-4 chimerisotype G2[11aaG4]-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687146

Category:

A

Anti-Human Complement C5 Reference Antibody (BOW080, RUO)

Target: C5/Complement C5
Target Alias Names: CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687116

Category:

A

Anti-Human Complement C5 Reference Antibody (CAN106, RUO)

Target: C5/Complement C5
Target Alias Names: CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687056

Category:

A

Anti-Human Complement C5 Reference Antibody (Crovalimab, RUO)

Target: C5/Complement C5
Target Alias Names: CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687026

Category:

A

Anti-Human Complement C5 Reference Antibody (Eculizumab, RUO)

Target: C5/Complement C5
Target Alias Names: CPAMD4, C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG2-G4-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HF687186

Category:

A

Anti-Human Complement C5 Reference Antibody (Greziprubart, RUO)

Target: C5a
Target Alias Name: C5a
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotypes/Mimetics: IgG1, Kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression