Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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7941-7950 of 11234 results

Catalogue Number:

bsm-61362R

Category:

NOS2 Recombinant Antibody

Target:	NOS2
Target Alias Names:	HEP-NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, iNOS, NOS2.
Species Reactivity:	Human, Mouse
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Naïve display libraries from animal B cells
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

bsm-61337R

Category:

Notch 4 Recombinant Antibody

Target:	NOTCH4
Target Alias Names:	NOTC4, hNotch4, INT3, Notch homolog 4.
Species Reactivity:	Human, Mouse
Applications:	Flow Cytometry, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Naïve display libraries from animal B cells
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

3439

Category:

Notch1 (C37C7) Rabbit mAb

References available

Target:	Notch1
Target Alias Names:	NOTCH1, Notch 1
Species Reactivity:	Human
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

3608

Category:

Notch1 (D1E11) XP® Rabbit mAb

347

References available

Target:	Notch1
Target Alias Names:	NOTCH1, Notch 1
Species Reactivity:	Human, Mouse, Rat
Applications:	Immunohistochemistry, Immunoprecipitation, Western Blot, Other
Other Application:	Chromatin IP
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

4380

Category:

Notch1 (D6F11) XP® Rabbit mAb

111

References available

Target:	Notch1
Target Alias Names:	NOTCH1, Notch 1
Species Reactivity:	Human, Mouse, Rat
Applications:	Flow Cytometry, Immunofluorescence, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

15004

Category:

Notch1 (D6F11) XP® Rabbit mAb (PE Conjugate)

Reference available

Target:	Notch1
Target Alias Names:	NOTCH1, Notch 1
Species Reactivity:	Human, Mouse, Rat
Application:	Flow Cytometry
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	PE
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

bsm-60871R

Category:

Notch1 Recombinant Antibody

Target:	Notch1
Target Alias Names:	Neurogenic locus notch homolog protein 1, Notch 1 extracellular truncation, Notch 1 intracellular domain, hN1, Lin-12, LIN12, MIS6, Motch A, mT14, Neurogenic locus notch homolog protein 1, Neurogenic locus notch protein homolog, NICD, Notch1 intracellular domain, NOTC1_HUMAN, Notch 1, NOTCH, Notch gene homolog 1 (Drosophila), Notch homolog 1 translocation associated (Drosophila), Notch homolog 1, translocation-associated (Drosophila), NOTCH, Drosophila, homolog of, 1, p300, TAN 1, TAN1, Translocation Associated Notch Homolog, Translocation Associated Notch Homolog, Translocation associated notch protein TAN 1, Translocation-associated notch protein TAN-1.
Species Reactivity:	Human, Mouse
Applications:	Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Naïve display libraries from animal B cells
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

4530

Category:

Notch2 (D67C8) XP® Rabbit mAb

References available

Target:	Notch2
Target Alias Names:	NOTCH2, Notch 2
Species Reactivity:	Human, Rat
Applications:	Immunofluorescence, Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

5732

Category:

Notch2 (D76A6) XP® Rabbit mAb

139

References available

Target:	Notch2
Target Alias Names:	NOTCH2, Notch 2
Species Reactivity:	Human, Mouse, Rat
Applications:	Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

70948

Category:

Notch2 (D76A6) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate)

Target:	Notch2
Target Alias Names:	NOTCH2, Notch 2
Species Reactivity:	Human, Mouse, Rat
Applications:	Flow Cytometry, Immunofluorescence
Type:	Primary Recombinant
Host Species:	Rabbit
Conjugate:	Alexa Fluor® 488
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

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