Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
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  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

70011-70020 of 70129 results

Catalogue Number:

PX-TA1977

Category:

G

Verzistobart Biosimilar – Anti-T-cell immunoglobulin mucin receptor 3 mAb – Research Grade

Target: T-cell immunoglobulin mucin receptor 3
Target Alias Name: anti-T-cell immunoglobulin mucin receptor 3/ HAVcr-2/ TIMD-3/ T-cell membrane protein 3/ HAVCR2/ Hepatitis A virus cellular receptor 2/ CD366/ TIMD3/ TIM-3/ TIM3/ T-cell immunoglobulin and mucin domain-containing protein 3
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1266

Category:

G

Vesencumab Biosimilar – Anti-Neuropilin-1/ NRP1/ VEGF165R extracellular domain mAb – Research Grade

Target: Neuropilin-1/ NRP1/ VEGF165R extracellular domain
Target Alias Name: Vesencumab/MNRP1685A/Neuropilin-1/ NRP1/ VEGF165R extracellular domain /anti-Neuropilin-1/ NRP1/ VEGF165R extracellular domain
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19418

Category:

G

VHH Isotype Control antibody (cAb-Lys2)

Target: Isotype Control
Species Reactivity: Other
Type: Primary Recombinant
Isotype/Mimetic: VHH
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19420

Category:

G

VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2)

Target: Isotype Control
Species Reactivity: Other
Type: Primary Recombinant
Isotype/Mimetic: VHH-hFc
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19421

Category:

G

VHH-hFc (IgG4-S228P) Isotype Control antibody (cAb-Lys2)

Target: Isotype Control
Species Reactivity: Other
Type: Primary Recombinant
Isotype/Mimetic: VHH-hFc
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19419

Category:

G

VHH-mFc Isotype Control antibody (cAb-Lys2)

Target: Isotype Control
Species Reactivity: Other
Type: Primary Recombinant
Isotype/Mimetic: VHH-mFc
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1564

Category:

G

Vibecotamab Biosimilar – Anti-CD3 epsilon/ IL3RA mAb – Research Grade

Target: CD3 epsilon/ IL3RA
Target Alias Name: Vibecotamab /XmAb14045/CD3 epsilon/ IL3RA/anti-CD3 epsilon/ IL3RA
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa / scFv-h-CH2-CH3
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1610

Category:

G

Vibostolimab Biosimilar – Anti-TIGIT/ VSIG9/ VSTM3 mAb – Research Grade

Target: TIGIT/ VSIG9/ VSTM3
Target Alias Name: Vibostolimab /MK-7684/TIGIT/ VSIG9/ VSTM3/anti-TIGIT/ VSIG9/ VSTM3
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2095

Category:

G

Vilamakitug Biosimilar – Anti-IL1F1 mAb – Research Grade

Target: IL1F1
Target Alias Name: anti-IL1F1/ Interleukin-1 alpha/ IL1A/ Hematopoietin-1/ IL-1 alpha
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2149

Category:

G

Vilastobart Biosimilar – Anti-CD152 mAb – Research Grade

Target: CD152
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: IgG1-fused prodomain kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression