Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

61-70 of 1245 results

Catalogue Number:

RHB73301

Category:

A

Anti-Human FGF19 Antibody (SAA1435)

Targets: FGF19, Fibroblast growth factor 19, FGF-19
Species Reactivity: Human
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHB95401

Category:

A

Anti-Human IFNG/IFN-gamma Antibody (SAA0266)

Targets: Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotypes/Mimetics: IgG1, lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHF88302

Category:

A

Anti-Human IL1RL1/ST2 antibody (C2244)

Targets: T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHF88301

Category:

A

Anti-Human IL1RL1/ST2 antibody (CNTO3914)

Targets: T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHF88303

Category:

A

Anti-Human IL1RL1/ST2 antibody (STLM208)

Targets: T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2
Species Reactivity: Human
Applications: ELISA, Flow Cytometry, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHC33101

Category:

A

Anti-Human INHBA Antibody (SAA0183)

Targets: EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHC82413

Category:

A

Anti-Human MAPT/Tau/PHF-tau Antibody (KW1)

Targets: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: VHH-Fc
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHC34201

Category:

A

Anti-Human MET/c-Met/HGFR Antibody (SAA0765)

Targets: Tyrosine-protein kinase Met, Hepatocyte growth factor receptor, Proto-oncogene c-Met, Scatter factor receptor, HGF receptor, SF receptor, HGF/SF receptor, MET, RCCP2
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHJ41001

Category:

A

Anti-Human NECTIN4 Antibody (P1E7)

Targets: LNIR, NECTIN4, PRR4 receptor-related protein 4, Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Nectin-4, PVRL4
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotypes/Mimetics: IgG1, lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

RHK09901

Category:

A

Anti-Human oxLDL Antibody (SAA0551)

Targets: oxidised LDL, oxidised form of low-density lipoprotein (LDL), oxidised low-density lipoproteins, oxidized low-density lipoprotein, oxidized low-density lipoproteins, OxLDL
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Naive display libraries derived from human B cells
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression