Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

48341-48350 of 62401 results

Catalogue Number:

PX-TA1357

Category:

G

Lumretuzumab Biosimilar – Anti-ERBB3 mAb – Research Grade

Target: ERBB3
Target Alias Name: Lumretuzumab/RG-7116/RO5479599/ERBB3/anti-ERBB3
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2125

Category:

G

Lumrotatug Biosimilar – Anti-Cyclic ADP-ribose hydrolase 1 mAb – Research Grade

Target: Cyclic ADP-ribose hydrolase 1
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

66472

Category:

D

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Lunatic Fringe (D6V2V) Rabbit mAb

2

References available

Target: LFNG
Target Alias Name: LFNG
Species Reactivity: Human, Mouse, Rat, Other
Applications: Immunoprecipitation, Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Rabbit
Animal-Derived Biomaterials Used: BSA
Sequence Available Yes
Original Discovery Method Immunization
Antibody/Binder Origins: Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation
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Catalogue Number:

PX-TA2126

Category:

G

Lunsekimig Biosimilar – Anti-IL13/ Albumin mAb – Research Grade

Target: IL13/ Albumin
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Ig single chain of 5 VH (sc-5-VH)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1434

Category:

G

Lupartumab Biosimilar – Anti-LYPD3 mAb – Research Grade

Target: LYPD3
Target Alias Name: Lupartumab/BAY 1112623/LYPD3/anti-LYPD3
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1682

Category:

G

Lusvertikimab Biosimilar – Anti-IL7R mAb – Research Grade

Target: IL7R
Target Alias Name: Lusvertikimab/LUSVERTIKIMAB/OSE-127/IL7R/anti-IL7R
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1440

Category:

G

Lutikizumab Biosimilar – Anti-IL1A / IL1B mAb – Research Grade

Target: IL1A / IL1B
Target Alias Name: Lutikizumab/ABT-981/IL1A / IL1B/anti-IL1A / IL1B
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: [VH-VH'-H-Gamma1-VL-VL'-C-kappa]-dimer
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2127

Category:

G

Luvagrobart Biosimilar – Anti-Beta-nerve growth factor mAb – Research Grade

Target: Beta-nerve growth factor
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1862

Category:

G

Luveltamab Biosimilar – Anti-FOLR1 mAb – Research Grade

Target: FOLR1
Target Alias Name: Luveltamab//FOLR1/anti-FOLR1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

79762

Category:

F

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LXR-α (E3D9B) Rabbit mAb

Target: LXR-alpha
Target Alias Names: NR1H3, LXR-alpha
Species Reactivity: Human
Application: Western Blot
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Rabbit
Animal-Derived Biomaterials Used: BSA
Sequence Available Yes
Original Discovery Method Immunization
Antibody/Binder Origins: Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation
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