Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

44941-44950 of 70091 results

Catalogue Number:

14938

Category:

Phospho-IKKα/β (Ser176/180) (16A6) Rabbit mAb (PE Conjugate)

References available

Target:	IKK-alpha (Ser176/Ser180) phosphate
Target Alias Names:	CHUK, IKKA
Species Reactivity:	Human, Mouse, Rat, Other
Application:	Flow Cytometry
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	PE
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

8766

Category:

Phospho-IKKε (Ser172) (D1B7) Rabbit mAb

References available

Target:	IKK-epsilon (Ser172) phosphate
Target Alias Names:	IKBKE, IKKE
Species Reactivity:	Human
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

8548

Category:

Phospho-IP3 Receptor (Ser1756) (D10E3) Rabbit mAb

References available

Target:	IP3R1 (Ser1764) phosphate
Target Alias Names:	ITPR1, IP3R1
Species Reactivity:	Human, Mouse, Rat
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

11927

Category:

Phospho-IRAK4 (Thr345/Ser346) (D6D7) Rabbit mAb

References available

Target:	IRAK4 (Thr345/Ser346) phosphate
Target Alias Name:	IRAK4
Species Reactivity:	Human
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

bsm-61238R

Category:

Phospho-IRE1 (Ser724) Recombinant Antibody

Target:	IRE1
Target Alias Names:	ERN1, ER to nucleus signalling 1, Inositol-requiring enzyme 1, Inositol-requiring protein 1, Ire1-alpha, IRE1a, HIRE1p, IRE1, Inositol-requiring 1, IRE1P.
Species Reactivity:	Human
Application:	Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Native display libraries from animal B cells
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

79945

Category:

Phospho-IRF-3 (Ser379) (E6F7Q) Rabbit mAb

References available

Target:	IRF-3 (Ser379) phosphate mouse
Target Alias Name:	IRF3
Species Reactivity:	Mouse
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

37829

Category:

Phospho-IRF-3 (Ser386) (E7J8G) XP® Rabbit mAb

References available

Target:	IRF-3 (Ser386) phosphate
Target Alias Name:	IRF3
Species Reactivity:	Human
Applications:	Flow Cytometry, Immunofluorescence, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

73981

Category:

Phospho-IRF-3 (Ser386) (E7J8G) XP® Rabbit mAb (Alexa Fluor® 488 Conjugate)

Reference available

Target:	IRF-3 (Ser386) phosphate
Target Alias Name:	IRF3
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	Alexa Fluor® 488
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

96421

Category:

Phospho-IRF-3 (Ser386) (E7J8G) XP® Rabbit mAb (Alexa Fluor® 647 Conjugate)

Reference available

Target:	IRF-3 (Ser386) phosphate
Target Alias Name:	IRF3
Species Reactivity:	Human
Application:	Flow Cytometry
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Conjugate:	Alexa Fluor® 647
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

4947

Category:

Phospho-IRF-3 (Ser396) (4D4G) Rabbit mAb

713

References available

Target:	IRF-3 (Ser396) phosphate
Target Alias Name:	IRF3
Species Reactivity:	Human, Mouse
Application:	Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

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