Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

4071-4080 of 4090 results

Catalogue Number:

PX-TA1472

Category:

G

Zanidatamab Biosimilar – Anti-ERBB2/ EGFR2/ CD340 mAb – Research Grade

Target: ERBB2/ EGFR2/ CD340
Target Alias Name: Zanidatamab /ZW-25/ZW25/ERBB2/ EGFR2/ CD340/anti-ERBB2/ EGFR2/ CD340
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa/scFv-h-CH2-CH3
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1152

Category:

G

Zanolimumab Biosimilar – Anti-CD4 mAb – Research Grade

Target: CD4
Target Alias Name: Zanolimumab/HuMax-CD4/CD4/anti-CD4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1741

Category:

G

Zansecimab Biosimilar – Anti-ANGPT2 mAb – Research Grade

Target: ANGPT2
Target Alias Name: Zansecimab/IMMUNOGLOBULIN G4 (229-PROLINE/235-ALANINE/236-ALANINE)/ ANTI-(HUMAN ANGIOPOIETIN 2) (HUMAN-MUS MUSCULUS MONOCLONAL LY3127804 .GAMMA.4-CHAIN)/ DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL LY3127804 .KAPPA.-CHAIN/ DIMER/ LY3127804/ LY-3127804/ANGPT2/anti-ANGPT2
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1921

Category:

G

Zatuximab Biosimilar – Anti-HER1 mAb – Research Grade

Target: HER1
Target Alias Name: anti-HER1/Receptor tyrosine-protein kinase erbB-1/Proto-oncogene c-ErbB-1/Epidermal growth factor receptor/EGFR/ERBB1/ERBB/Futuximab/ DS 992/ Sym 004 (combination of modotuximab and futuximab)
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2152

Category:

G

Zeleciment Biosimilar – Anti-Transferrin receptor protein 1 mAb – Research Grade

Target: Transferrin receptor protein 1
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: immunoglobulin Fab-G1kappa (VH-CH1_L-kappa)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1612

Category:

G

Zelminemab Biosimilar – Anti-ADCYAP1R1 mAb – Research Grade

Target: ADCYAP1R1
Target Alias Name: Zelminemab /AMG-301/ADCYAP1R1/anti-ADCYAP1R1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1742

Category:

G

Zeluvalimab Biosimilar – Anti-PDCD1 mAb – Research Grade

Target: PDCD1
Target Alias Name: Zeluvalimab/AMG 404/IMMUNOGLOBULIN G1 (295-CYSTEINE/300-GLYCINE/305-CYSTEINE)/ ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN MONOCLONAL 20C1.009 MAB .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL 20C1.009 MAB .KAPPA.-CHAIN/ DIMER/ AMG-404/PDCD1/anti-PDCD1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1493

Category:

G

Zenocutuzumab Biosimilar – Anti-ERBB2/ ERBB3 mAb – Research Grade

Target: ERBB2/ ERBB3
Target Alias Name: Zenocutuzumab/MCLA-128/PB4188/R040517/ERBB2/ ERBB3/anti-ERBB2/ ERBB3
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2097

Category:

G

Zeripatamig Biosimilar – Anti-CD47 and CD19 mAb – Research Grade

Target: CD47 and CD19
Target Alias Name: anti-CD47/ IAP/ MER6/ OA3/ CD19
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa/lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2098

Category:

G

Zifibancimig Biosimilar – Anti-ANG-2 and VEGFA mAb – Research Grade

Target: ANG-2 and VEGFA
Target Alias Name: anti-ANG-2/ ANGPT2/ Angiopoietin-2/ VEGFA/ VEGF alpha
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: immunoglobulin Fab G1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression