Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
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  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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40311-40320 of 41000 results

Catalogue Number:

MS739040

Category:

A

InVivoMAb Anti-Mouse TIGIT Antibody (10A7)

Target: TIGIT
Target Alias Names: T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3
Species Reactivity: Mouse
Applications: ELISA, Flow Cytometry, Other
Type: Primary Recombinant
Isotypes/Mimetics: IgG2a, kappa
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MS739020

Category:

A

InVivoMAb Anti-Mouse TIGIT Antibody (1B4)

Target: TIGIT
Target Alias Names: T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotypes/Mimetics: IgG2a, kappa
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MS739030

Category:

A

InVivoMAb Anti-Mouse TIGIT Antibody (4D4)

Target: TIGIT
Target Alias Names: T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotypes/Mimetics: IgG2a, kappa
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MS739010

Category:

A

InVivoMAb Anti-Mouse TIGIT&PD-L1/B7-H1 Antibody (Iv0247)

Target: TIGIT & CD274/PD-L1
Target Alias Names: Bispecific, T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, Tigit, Vstm3, Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MX892010

Category:

A

InVivoMAb Anti-Mouse TIGIT&PD-L1/B7-H1 Antibody (Iv0258)

Target: CD172a/SIRPA
Target Alias Names: Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, mSIRP-alpha1, p84, CD172a, Sirpa, Bit, Myd1, Ptpns1, Shps1, Sirp
Species Reactivity: Mouse
Applications: ELISA, Other
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Rat
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MV029010

Category:

A

InVivoMAb Anti-Mouse TIM-3 Antibody (B8.2C12)

Target: CD366/HAVCR2/TIM-3
Target Alias Names: CD366, HAVcr-2, Havcr2, Hepatitis A virus cellular receptor 2 homolog, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, TIM-3, TIMD-3, Tim3, Timd3
Species Reactivity: Mouse
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotypes/Mimetics: IgG1, kappa
Host Species: Rat
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MT439010

Category:

A

InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6)

Target: CD254/RANKL/TNFSF11
Target Alias Names: Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form, Tnfsf11, Opgl, Rankl, Trance
Species Reactivity: Mouse
Applications: ELISA, Other
Type: Primary Recombinant
Isotype/Mimetic: VHH-mFc
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

ME056010

Category:

A

InVivoMab Anti-Mouse TYRP1 & CD3 epsilon Antibody (145-2C11 & TA99)

Target: TYRP1 & CD3 epsilon
Target Alias Names: 5, 6-dihydroxyindole-2-carboxylic acid oxidase, Brown locus protein, Catalase B, DHICA oxidase, EC:1.14.18.-, TRP, TRP-1, TRP1, Tyrosinase-related protein 1, Tyrp-1, Tyrp1, CD3e, Cd3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotypes/Mimetics: IgG2a, kappa (LALA-PG)
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MW754010

Category:

A

InVivoMAb Anti-Mouse TYRP1&CD3 epsilon Antibody (Iv0236)

Target: TRP-1 & CD3e
Target Alias Names: Bispecific, 5, 6-dihydroxyindole-2-carboxylic acid oxidase, Glycoprotein 75, CAS2, TYRP1, TRP-1, TYRRP, TRP1, Catalase B, TYRP, Melanoma antigen gp75, TRP, DHICA oxidase, Tyrosinase-related protein 1, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, Cd3e
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotypes/Mimetics: IgG2a, kappa
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

MW754020

Category:

A

InVivoMAb Anti-Mouse TYRP1&CD47 Antibody (Iv0237)

Target: TRP-1 & CD47/MER6
Target Alias Names: Bispecific, 5, 6-dihydroxyindole-2-carboxylic acid oxidase, Glycoprotein 75, CAS2, TYRP1, TRP-1, TYRRP, TRP1, Catalase B, TYRP, Melanoma antigen gp75, TRP, DHICA oxidase, Tyrosinase-related protein 1, Leukocyte surface antigen CD47, Integrin-associated protein, IAP, CD47, Cd47
Species Reactivity: Mouse
Application: Other
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Mouse
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression