Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
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  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3971-3980 of 4090 results

Catalogue Number:

PX-TA1728

Category:

G

Tozorakimab Biosimilar – Anti-IL33 mAb – Research Grade

Target: IL33
Target Alias Name: Tozorakimab/IMMUNOGLOBULIN G1/ ANTI-(HUMAN INTERLEUKIN 33) (HUMAN MONOCLONAL MEDI3506 .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL MEDI3506 .LAMBDA.-CHAIN/ DIMER/ MEDI-3506/IL33/anti-IL33
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1974

Category:

G

Trabikibart Biosimilar – Anti-Cytokine receptor common subunit beta mAb – Research Grade

Target: Cytokine receptor common subunit beta
Target Alias Name: anti-Cytokine receptor common subunit beta/ IL3RB/ IL5RB/ CDw131/ CD131/ CSF2RB/ GM-CSF/IL-3/IL-5 receptor common beta subunit
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1126

Category:

G

Tralokinumab Biosimilar – Anti-IL13 mAb – Research Grade

Target: IL13
Target Alias Name: Tralokinumab/CAT-354/IL13/anti-IL13
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1005

Category:

G

Trastuzumab Biosimilar – Anti-HER2 mAb – Research Grade

Target: HER2
Target Alias Name: Trastuzumab/Trastuzumab/HER2/anti-HER2
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2143

Category:

G

Traxivitug Biosimilar – Anti-Major capsid protein VP1 mAb – Research Grade

Target: Major capsid protein VP1
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1263

Category:

G

Tregalizumab Biosimilar – Anti-CD4 mAb – Research Grade

Target: CD4
Target Alias Name: Tregalizumab/BT-061/ hB-F5/ hBF5(H37L_L4M)/CD4/anti-CD4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1177

Category:

G

Tremelimumab Biosimilar – Anti-CTLA4/ CD152 mAb – Research Grade

Target: CTLA4/ CD152
Target Alias Name: Tremelimumab/Ticilimumab/ CP-675/CP-675/206/CP-675206 clone 11.2.1/CTLA4/ CD152/anti-CTLA4/ CD152
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1388

Category:

G

Trevogrumab Biosimilar – Anti-MSTN/ GDF8 mAb – Research Grade

Target: MSTN/ GDF8
Target Alias Name: Trevogrumab/REGN-1033/ REGN1033/ SAR-391786/MSTN/ GDF8/anti-MSTN/ GDF8
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1789

Category:

G

Trinbelimab Biosimilar – Anti-Rhesus D antigen mAb – Research Grade

Target: Rhesus D antigen
Target Alias Name: Trinbelimab/r Anti-D/ r-anti-D/Rhesus D antigen/anti-Rhesus D antigen
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda3
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1887

Category:

G

Trontinemab Biosimilar – Anti-APP Abeta 1-40/ 42/TFRC mAb – Research Grade

Target: APP Abeta 1-40/ 42/TFRC
Target Alias Name: Trontinemab//APP Abeta 1-40/ 42/TFRC/anti-APP Abeta 1-40/ 42/TFRC
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa/IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression