Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

3911-3920 of 4090 results

Catalogue Number:

PX-TA1554

Category:

Tamrintamab Biosimilar – Anti-DPEP3/ MBD3 mAb – Research Grade

Target:	DPEP3/ MBD3
Target Alias Name:	Tamrintamab /SC-003 mAb/SC-Mab003/SC34.28ss1/DPEP3/ MBD3/anti-DPEP3/ MBD3
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1414

Category:

Tamtuvetmab Biosimilar – Anti-NGF/ NGFB mAb – Research Grade

Target:	NGF/ NGFB
Target Alias Name:	Tamtuvetmab/AT-005/AT005/NGF/ NGFB/anti-NGF/ NGFB
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-nd
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1164

Category:

Tanezumab Biosimilar – Anti-IGHE mAb – Research Grade

Target:	IGHE
Target Alias Name:	Tanezumab/PF-04383119/RN624/IGHE/anti-IGHE
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1201

Category:

Taplitumomab Biosimilar – Anti-CD19 mAb – Research Grade

Target:	CD19
Target Alias Name:	Taplitumomab//CD19 /anti-CD19
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1780

Category:

Tarcocimab Biosimilar – Anti-VEGFA mAb – Research Grade

Target:	VEGFA
Target Alias Name:	Tarcocimab/OG1953/VEGFA/anti-VEGFA
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1326

Category:

Tarextumab Biosimilar – Anti-CD52 mAb – Research Grade

Target:	CD52
Target Alias Name:	Tarextumab/OMP-59R5/CD52/anti-CD52
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-kappa-lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1720

Category:

Tarlatamab Biosimilar – Anti-DLL3/CD3E mAb – Research Grade

Target:	DLL3/CD3E
Target Alias Name:	Tarlatamab/IMMUNOGLOBULIN SCFV-SCFV-SCFC/ ANTI-(HOMO SAPIENS DLL3 (DELTA-LIKE LIGAND 3)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON/ LEU-4))/ MONOCLONAL ANTIBODY SINGLE CHAIN (SCFV)2-SCFC/ BISPECIFIC/DLL3/CD3E/anti-DLL3/CD3E
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	Bispecific scFv/Kappa/Lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2088

Category:

Tarperprumig Biosimilar – Anti-CFP and ALB mAb – Research Grade

Target:	CFP and ALB
Target Alias Name:	anti-CFP/ ALB/ SAH
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	immunoglobulin single chain VH-VH'
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1615

Category:

Tavolimab Biosimilar – Anti-TNF- SF4 receptor I mAb – Research Grade

Target:	TNF- SF4 receptor I
Target Alias Name:	Tavolimab/MEDI0562/TNF- SF4 receptor I/anti-TNF- SF4 receptor I
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	TBP-1:tumor necrosis factor (TNF) binding protein variant 1
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1721

Category:

Tebentafusp Biosimilar – Anti-CD3E mAb – Research Grade

Target:	CD3E
Target Alias Name:	Tebentafusp/IMCGP 100/ T CELL RECEPTOR .ALPHA. CHAIN (SYNTHETIC HUMAN) FUSION PROTEIN WITH T CELL RECEPTOR .BETA. CHAIN (SYNTHETIC HUMAN) FUSION PROTEIN WITH IMMUNOGLOBULIN/ ANTI-(HUMAN CD3 ANTIGEN) (SYNTHETIC SCFV FRAGMENT)/CD3E/anti-CD3E
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	Kappa/ Strep + His-Tag
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 3911-3920 of 4090 results

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