Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

3791-3800 of 4090 results

Catalogue Number:

PX-TA1880

Category:

Retlirafusp Biosimilar – Anti-CD274 mAb – Research Grade

Target:	CD274
Target Alias Name:	Retlirafusp//CD274/anti-CD274
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4 Kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1710

Category:

Revdofilimab Biosimilar – Anti-TNFRSF4 mAb – Research Grade

Target:	TNFRSF4
Target Alias Name:	Revdofilimab/ABBV368/ HUMANIZED/ RECOMBINANT MONOCLONAL ANTIBODY THAT BINDS TO CELL SURFACE EXPRESSED /OX40 (TNF RECEPTOR SUPERFAMILY MEMBER 4)/ ANTI-OX40 AGONIST MONOCLONAL ANTIBODY ABBV-368/ PR1628103/ PR-1628103/TNFRSF4/anti-TNFRSF4
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1/Kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2135

Category:

Rezetamig Biosimilar – Anti-Sialic acid-binding Ig-like lectin 2/ T-cell surface glycoprotein CD3 epsilon chain mAb – Research Grade

Target:	Sialic acid-binding Ig-like lectin 2/ T-cell surface glycoprotein CD3 epsilon chain
Species Reactivity:	Human
Application:	ELISA
Type:	Primary Recombinant
Isotype/Mimetic:	immunoglobulin half G4-kappa_G4(VH-h-CH2-CH3)
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2136

Category:

Rezorstobart Biosimilar – Anti-CLEC5B mAb – Research Grade

Target:	CLEC5B
Species Reactivity:	Human
Application:	ELISA
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1970

Category:

Riliprubart Biosimilar – Anti-C1 esterase mAb – Research Grade

Target:	C1 esterase
Target Alias Name:	anti-C1 esterase/ Complement C1s subcomponent/ C1S/ Complement component 1 subcomponent s
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1214

Category:

Rilotumumab Biosimilar – Anti-HGF mAb – Research Grade

Target:	HGF
Target Alias Name:	Rilotumumab//HGF/anti-HGF
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2087

Category:

Riltovetbart Biosimilar – Anti-canis lupus IL31 mAb – Research Grade

Target:	canis lupus IL31
Target Alias Name:	anti-canis lupus IL31
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2078

Category:

Rilvegostomig Biosimilar – Anti-PD-1 and TIGIT mAb – Research Grade

Target:	PD-1 and TIGIT
Target Alias Name:	anti-PD1/ Programmed cell death protein 1/ Protein PD-1/ hPD-1/ PDCD1/ CD279/ TIGIT
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa/lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1804

Category:

Rimteravimab Biosimilar – Anti-Spike RBD mAb – Research Grade

Target:	Spike RBD
Target Alias Name:	Rimteravimab/VHH-72-Fc/ XVR011/Spike RBD/anti-Spike RBD
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	[VH-h-CH2-CH3]-dimer
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1400

Category:

Rinucumab Biosimilar – Anti-PDGFRB/ PDGFR-1/ CD140b mAb – Research Grade

Target:	PDGFRB/ PDGFR-1/ CD140b
Target Alias Name:	Rinucumab/REGN-2176/REGN-2176-3 (combination of aflibercept and ricunumab)/REGN2176/PDGFRB/ PDGFR-1/ CD140b/anti-PDGFRB/ PDGFR-1/ CD140b
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 3791-3800 of 4090 results

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