Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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3781-3790 of 5093 results

Catalogue Number:

AP1521

Category:

Phospho-ErbB4/HER4-Y1284 Rabbit mAb

Target:	ERBB4
Target Alias Names:	HER4, ALS19, p180erbB4
Species Reactivity:	Human
Applications:	Immunofluorescence, Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP0485

Category:

Phospho-ERK1-T202 + ERK2-T185 Rabbit mAb

References available

Target:	ERK1/ERK2
Target Alias Names:	H3.4, H3/g, H3FT, H3t, H3/A, H3FA, ERK1 / ERK2, Phospho-ERK1-T202 + ERK2-T185
Species Reactivity:	Human, Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP0974

Category:

Phospho-ERK1-T202/Y204 + ERK2-T185/Y187 Rabbit mAb

References available

Target:	MAPK1/MAPK3
Target Alias Names:	ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK, Phospho-ERK1-T202/Y204 + ERK2-T185/Y187
Species Reactivity:	Human, Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1004

Category:

Phospho-ESRα-S118 Rabbit mAb

Reference available

Target:	ESR1
Target Alias Names:	ER, ESR, Era, ESRA, ESTRR, NR3A1, Phospho-ESRα-S118
Species Reactivity:	Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

70303

Category:

Phospho-Ezh2 (Thr311) (F1K1B) Rabbit mAb

Target:	EZH2 (Thr311) phosphate
Target Alias Name:	EZH2
Species Reactivity:	Human, Mouse, Rat, Other
Application:	Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

45153

Category:

Phospho-Ezh2 (Thr345) (E7T7K) Rabbit mAb

Target:	EZH2 (Thr345) phosphate
Target Alias Name:	EZH2
Species Reactivity:	Human, Mouse, Rat, Other
Applications:	Immunoprecipitation, Western Blot, Other
Other Applications:	Chromatin IP, Chromatin IP-seq, CUT&RUN
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1447

Category:

Phospho-FAK-Y397 Rabbit mAb

References available

Target:	PTK2
Target Alias Names:	FAK, FADK, FAK1, FRNK, FADK 1, PPP1R71, p125FAK, pp125FAK, Phospho-FAK-Y397
Species Reactivity:	Human
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1547

Category:

Phospho-FAK-Y576/Y577 Rabbit mAb

Target:	PTK2
Target Alias Names:	FAK, FADK, FAK1, FRNK, FADK 1, PPP1R71, p125FAK, pp125FAK
Species Reactivity:	Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

89678

Category:

Phospho-FAM134B (Ser151) (F8R4D) Rabbit mAb

Target:	FAM134B (Ser151) phosphate
Target Alias Names:	RETREG1, FAM134B
Species Reactivity:	Human
Applications:	Immunoprecipitation, Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

38013

Category:

Phospho-Fgr (Tyr412) (E3R7L) Rabbit mAb

Target:	FGR (Tyr412) phosphate
Target Alias Name:	FGR
Species Reactivity:	Human
Application:	Western Blot
Type:	Primary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Animal-Derived Biomaterials Used:	BSA
Sequence Available	Yes
Original Discovery Method	Immunization
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Viewing 3781-3790 of 5093 results

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