Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3711-3720 of 4090 results

Catalogue Number:

PX-TA1706

Category:

G

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Pucotenlimab Biosimilar – Anti-PDCD1 mAb – Research Grade

Target: PDCD1
Target Alias Name: Pucotenlimab/HUMANIZED PD-1 BLOCKING ANTIBODY HX-008/ IMMUNOGLOBULIN G4 (252-THERONINE/306-PROLINE/432-ALANINE)/ ANTI-(HUMAN PROGRAMMED CELL DEATH 1) (HUMAN-MUS MUSCULUS MONOCLONAL HX008 .GAMMA.4-CHAIN)/ DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL HX008 .KAPPA.-CHAIN/ DIMER/PDCD1/anti-PDCD1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1786

Category:

G

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Pulocimab Biosimilar – Anti-VEGFR2 mAb – Research Grade

Target: VEGFR2
Target Alias Name: Pulocimab/AK 109/ AK-109/ AK109/VEGFR2/anti-VEGFR2
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

FHK25310-100

Category:

G

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Purified Human AS Fc Block„¢ (SAA0280)

Target: Fc Block
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/ kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

FMK25210-100

Category:

G

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Purified Mouse Anti-Mouse CD16/CD32 (Mouse AS Fc Block„¢) (2.4G2)

Target: CD16/CD32
Species Reactivity: Mouse
Type: Primary Recombinant
Isotype/Mimetic: IgG1/ kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1964

Category:

G

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Puxitatug Biosimilar – Anti-V-set domain-containing T-cell activation inhibitor 1 mAb – Research Grade

Target: V-set domain-containing T-cell activation inhibitor 1
Target Alias Name: anti-V-set domain-containing T-cell activation inhibitor 1/ B7h.5/ B7 homolog 4/ B7-H4/ T-cell costimulatory molecule B7x/ B7H4/ VTCN1/ Protein B7S1/ Immune costimulatory protein B7-H4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1707

Category:

G

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Quavonlimab Biosimilar – Anti-CTLA4 mAb – Research Grade

Target: CTLA4
Target Alias Name: Quavonlimab/IMMUNOGLOBULIN G1/ ANTI-(HUMAN CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4) (HUMAN-MUS MUSCULUS MONOCLONAL M3 .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL M3 .KAPPA.-CHAIN/ DIMER/ IMMUNOGLOBULIN G1-KAPPA/ ANTI-(HOMO SAPIENS CTLA4 (CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED PROTEIN 4/ CD152))/ HUMANIZED MONOCLONAL ANTIBODY/MK-1308A/CTLA4/anti-CTLA4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1572

Category:

G

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Quetmolimab Biosimilar – Anti-CX3CL1 mAb – Research Grade

Target: CX3CL1
Target Alias Name: Quetmolimab /E-6011/CX3CL1/anti-CX3CL1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1283

Category:

G

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Quilizumab Biosimilar – Anti-IGHE mAb – Research Grade

Target: IGHE
Target Alias Name: Quilizumab/47H4/Anti-M1 prime/MEMP1972A/RG-7449/IGHE/anti-IGHE
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1785

Category:

G

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Quisovalimab Biosimilar – Anti-CD258 mAb – Research Grade

Target: CD258
Target Alias Name: Quisovalimab/AEVI-002/ CERC-002/ F-19/ MDGN-002/ SAR-252067/CD258/anti-CD258
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PTX17968

Category:

G

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Rabbit IgG Isotype Control Antibody (HyHEL-10)

Target: Isotype Control
Species Reactivity: Other
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Rabbit
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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