Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3691-3700 of 4090 results

Catalogue Number:

PX-TA1923

Category:

G

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Pogalizumab Biosimilar – Anti-ACT35 antigen mAb – Research Grade

Target: ACT35 antigen
Target Alias Name: anti-ACT35 antigen/TXGP1L/TAX transcriptionally-activated glycoprotein 1 receptor/Tumor necrosis factor receptor superfamily member 4/TNFRSF4/OX40L receptor/CD134/Vonlerolizumab/ MOXR-0916/ MOXR0916/ RG-7888/ RO7021608
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1317

Category:

G

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Polatuzumab Biosimilar – Anti-CD79B(CD79b/ B29/ IGB/ Ig-beta) mAb – Research Grade

Target: CD79B(CD79b/ B29/ IGB/ Ig-beta)
Target Alias Name: Polatuzumab//CD79B(CD79b/ B29/ IGB/ Ig-beta)/anti-CD79B(CD79b/ B29/ IGB/ Ig-beta)
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA2082

Category:

G

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Polzastobart Biosimilar – Anti-ILT-4 mAb – Research Grade

Target: ILT-4
Target Alias Name: anti-ILT-4/ CD85 antigen-like family member D/ Monocyte/macrophage immunoglobulin-like receptor 10/ MIR-10/ ILT4/ LIR-2/ Immunoglobulin-like transcript 4/ MIR10/ CD85d/ Leukocyte immunoglobulin-like receptor subfamily B member 2/ Leukocyte immunoglobulin-like receptor 2/ LIR2/ LILRB2
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1261

Category:

G

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Ponezumab Biosimilar – Anti-APP Abeta40 mAb – Research Grade

Target: APP Abeta40
Target Alias Name: Ponezumab/PF-04360365/RN-1219/clone 9TL/APP Abeta40/anti-APP Abeta40
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1704

Category:

G

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Ponsegromab Biosimilar – Anti-GDF15 mAb – Research Grade

Target: GDF15
Target Alias Name: Ponsegromab/IMMUNOGLOBULIN G1 (237-ALANINE/238-ALANINE/240-ALANINE)/ ANTI-(HUMAN GROWTH DIFFERENTIATION FACTOR 15) (HUMAN-MUS MUSCULUS MONOCLONAL PF-06946860 .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL PF-06946860 .KAPPA.-CHAIN/ DIMER/GDF15/anti-GDF15
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1469

Category:

G

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Porgaviximab Biosimilar – Anti-Zaire Ebola virus mAb – Research Grade

Target: Zaire Ebola virus
Target Alias Name: Porgaviximab/c2G4-N/Zaire Ebola virus/anti-Zaire Ebola virus
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA2083

Category:

G

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Porustobart Biosimilar – Anti-CD152 mAb – Research Grade

Target: CD152
Target Alias Name: anti-CD152/ Cytotoxic T-lymphocyte protein 4/ CTLA-4/ CTLA4/ Cytotoxic T-lymphocyte-associated antigen 4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: Ig gamma1 VH-h-CH2-CH3 dimer
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1877

Category:

G

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Posdinemab Biosimilar – Anti-MAPT mAb – Research Grade

Target: MAPT
Target Alias Name: Posdinemab//MAPT/anti-MAPT
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PTX18660-100

Category:

G

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POSTN / OSF-2 Monoclonal Monoclonal Antibody 2F8

Target: POSTN
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Mouse
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PTX18661-100

Category:

G

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POSTN / OSF-2 Monoclonal Monoclonal Antibody 5G4

Target: POSTN
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Mouse
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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