Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3451-3460 of 4090 results

Catalogue Number:

PX-TA1595

Category:

G

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Mavezelimab Biosimilar – Anti-LAG3/ CD223 mAb – Research Grade

Target: LAG3/ CD223
Target Alias Name: Mavezelimab /MK-4280/LAG3/ CD223/anti-LAG3/ CD223
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1241

Category:

G

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Mavrilimumab Biosimilar – Anti-CSF2RA/ CD116 mAb – Research Grade

Target: CSF2RA/ CD116
Target Alias Name: Mavrilimumab/CAM-3001/CSF2RA/ CD116 /anti-CSF2RA/ CD116
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-lambda2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1794

Category:

G

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Mazorelvimab Biosimilar – Anti-G Glycoprotein mAb – Research Grade

Target: G Glycoprotein
Target Alias Name: Mazorelvimab/CTB 012/ CTB-012/ CTB012/ SYN023/G Glycoprotein/anti-G Glycoprotein
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1928

Category:

G

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MDX-1342 Biosimilar – Anti-CD19 mAb – Research Grade

Target: CD19
Target Alias Name: anti-CD19/ Differentiation antigen CD19/ T-cell surface antigen Leu-12/ B-lymphocyte antigen CD19/ B-lymphocyte surface antigen B4/
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1864

Category:

G

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Mecbotamab Biosimilar – Anti-AXL mAb – Research Grade

Target: AXL
Target Alias Name: Mecbotamab//AXL/anti-AXL
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1898

Category:

G

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MEDI3185 Biosimilar – Anti-Stromal cell-derived factor 1 receptor mAb – Research Grade

Target: Stromal cell-derived factor 1 receptor
Target Alias Name: anti-Stromal cell-derived factor 1 receptor/LCR1/HM89/LPS-associated protein 3/LAP-3/CXC-R4/CXCR-4/SDF-1 receptor/CD184/NPYRL/LESTR/Fusin/FB22/C-X-C chemokine receptor type 4/CXCR4/Lipopolysaccharide-associated protein 3/Leukocyte-derived seven transmembrane domain receptor/
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1865

Category:

G

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Melredableukin Biosimilar – Anti-Non-Binding mAb – Research Grade

Target: Non-Binding
Target Alias Name: Melredableukin//Non-Binding/anti-Non-Binding
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1683

Category:

G

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Melrilimab Biosimilar – Anti-IL1RL1 mAb – Research Grade

Target: IL1RL1
Target Alias Name: Melrilimab/CNTO-7160/GSK3772847/ GSK-3772847/ IMMUNOGLOBULIN IGG2/ ANTI-(HUMAN INTERLEUKIN 1 RECEPTOR-LIKE 1 PROTEIN) (HUMAN MONOCLONAL GSK3772847 .GAMMA.2-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL GSK3772847 .KAPPA.-CHAIN/ DIMER/IL1RL1/anti-IL1RL1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1619

Category:

G

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Meplazumab Biosimilar – Anti-CD147 mAb – Research Grade

Target: CD147
Target Alias Name: Meplazumab/Basigin/BSG/5F7/CD147/EMMPRIN/M6/OK/TCSF/CD147/anti-CD147
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1062

Category:

G

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Mepolizumab Biosimilar – Anti-IL5 mAb – Research Grade

Target: IL5
Target Alias Name: Mepolizumab/SB-240563/IL5/anti-IL5
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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