Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3391-3400 of 4090 results

Catalogue Number:

PX-TA1134

Category:

G

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Lerdelimumab Biosimilar – Anti-TGFB2 mAb – Research Grade

Target: TGFB2
Target Alias Name: Lerdelimumab/CAT-152/Trabio/TGFB2/anti-TGFB2
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-nd
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1511

Category:

G

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Leronlimab Biosimilar – Anti-CCR5/ CD195 mAb – Research Grade

Target: CCR5/ CD195
Target Alias Name: Leronlimab/HuPRO-140/PA-14/PRO-140/CCR5/ CD195/anti-CCR5/ CD195
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1858

Category:

G

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Lesabelimab Biosimilar – Anti-CD274 mAb – Research Grade

Target: CD274
Target Alias Name: Lesabelimab//CD274/anti-CD274
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1462

Category:

G

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Lesofavumab Biosimilar – Anti-hemagglutinin mAb – Research Grade

Target: hemagglutinin
Target Alias Name: Lesofavumab/MHAB5553A/RG70026/RO7045557/hemagglutinin/anti-hemagglutinin
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1678

Category:

G

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Letaplimab Biosimilar – Anti-CD47 mAb – Research Grade

Target: CD47
Target Alias Name: Letaplimab/HUMAN ANTI-CD47 MONOCLONAL ANTIBODY (IBI-188)/IMMUNOGLOBULIN G4 (223-PROLINE/229-ALANINE/230-ALANINE/DE-C-TERMINAL-LYSINE)/ ANTI-(HUMAN CD47 ANTIGEN) (HUMAN MONOCLONAL IBI188 .GAMMA.4-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL IBI188 .KAPPA.-CHAIN/ DIMER/CD47/anti-CD47
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1459

Category:

G

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Letolizumab Biosimilar – Anti-CD40LG/ CD154 mAb – Research Grade

Target: CD40LG/ CD154
Target Alias Name: Letolizumab/BMS-986004/CD40LG/ CD154/anti-CD40LG/ CD154
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: (VH-CH2-CH3)2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA2041

Category:

G

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Leukotuximab Biosimilar – Anti-GPL115 mAb – Research Grade

Target: GPL115
Target Alias Name: anti-GPL115/ Leukocyte sialoglycoprotein/ Leukosialin/ Sialophorin/ SPN/ Galactoglycoprotein/ CD43/ CD43ct/ CD43-ct/ GALGP
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1545

Category:

G

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Levilimab Biosimilar – Anti-IL6R mAb – Research Grade

Target: IL6R
Target Alias Name: Levilimab /BCD-089/IL6R/anti-IL6R
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1135

Category:

G

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Lexatumumab Biosimilar – Anti-TNFRSF10B/ CD262 mAb – Research Grade

Target: TNFRSF10B/ CD262
Target Alias Name: Lexatumumab/HGS-ETR2/TNFRSF10B/ CD262/anti-TNFRSF10B/ CD262
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1189

Category:

G

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Libivirumab Biosimilar – Anti-HBV/ HBsAg mAb – Research Grade

Target: HBV/ HBsAg
Target Alias Name: Libivirumab/17.1.41/HepeX-B-(combination of exbivirumab and libivirumab)/HBV/ HBsAg/anti-HBV/ HBsAg
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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