Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3391-3400 of 41000 results

Catalogue Number:

HC336066

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (EU101, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336116

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Evunzekibart, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336126

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Exlinkibart, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336056

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (HOT-1030, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336076

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (LVGN6051, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336026

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Urelumab, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336016

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (Utomilumab, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG2-lambda
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336046

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9 Reference Antibody (YH-004, RUO)

Target: CD137/4-1BB
Target Alias Names: Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HB996316

Category:

A

Anti-Human 4-1BB Ligand/TNFSF9&CD19 Reference Antibody (Ensomafusp Alfa, RUO)

Target: CD19 & CD137/TNFRSF9
Target Alias Names: CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HC336236

Category:

A

Anti-Human 4-1BB/TNFRSF9/CD137 & CD3 epsilon & DLL3 Reference Antibody (Clesitamig, RUO)

Target: CD137/4-1BB/TNFRSF9&CD3E&DLL3
Target Alias Name: CD137/4-1BB/TNFRSF9&CD3E&DLL3
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: IgG[(V-kappa-G4CH1-G1h-H-gamma1_L-kappa)_Lkappa)]_(H-gamma1_L-kappa)
Host Species: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Preservative-free, Glycerol-free, Low Endotoxin
Animal-Derived Biomaterials Used: No
Sequence Available No
Original Discovery Method Unknown
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression