Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

3351-3360 of 4090 results

Catalogue Number:

PX-TA1178

Category:

G

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Iratumumab Biosimilar – Anti-TNFRSF8/ CD30 mAb – Research Grade

Target: TNFRSF8/ CD30
Target Alias Name: Iratumumab/MDX-060/TNFRSF8/ CD30/anti-TNFRSF8/ CD30
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1377

Category:

G

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Isatuximab Biosimilar – Anti-CD38 mAb – Research Grade

Target: CD38
Target Alias Name: Isatuximab/SAR-650984/hu38SB19/CD38/anti-CD38
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1503

Category:

G

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Iscalimab Biosimilar – Anti-CD40/ TNFRSF5 mAb – Research Grade

Target: CD40/ TNFRSF5
Target Alias Name: Iscalimab/CFZ-533/NVP-CFZ533/OM11-62MF/CD40/ TNFRSF5/anti-CD40/ TNFRSF5
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1850

Category:

G

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Isecarosmab Biosimilar – Anti-ADAMTSL5/ALB mAb – Research Grade

Target: ADAMTSL5/ALB
Target Alias Name: Isecarosmab//ADAMTSL5/ALB/anti-ADAMTSL5/ALB
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: Igna/na na/na
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1851

Category:

G

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Ispectamab Biosimilar – Anti-TNFRSF17 mAb – Research Grade

Target: TNFRSF17
Target Alias Name: Ispectamab//TNFRSF17/anti-TNFRSF17
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1381

Category:

G

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Istiratumab Biosimilar – Anti-ERBB3/ IGF1R/ CD221 mAb – Research Grade

Target: ERBB3/ IGF1R/ CD221
Target Alias Name: Istiratumab/MM-005/MM-141/ERBB3/ IGF1R/ CD221/anti-ERBB3/ IGF1R/ CD221
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa -[scFv]2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1852

Category:

G

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Itepekimab Biosimilar – Anti-IL33 mAb – Research Grade

Target: IL33
Target Alias Name: Itepekimab//IL33/anti-IL33
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4 Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1246

Category:

G

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Itolizumab Biosimilar – Anti-CD6 mAb – Research Grade

Target: CD6
Target Alias Name: Itolizumab/T1h/CD6/anti-CD6
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1774

Category:

G

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Ivicentamab Biosimilar – Anti-CD37 mAb – Research Grade

Target: CD37
Target Alias Name: Ivicentamab/DuoHexaBody-CD37/ GEN 3009/ GEN-3009/ GEN3009/CD37/anti-CD37
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1763

Category:

G

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Ivonescimab Biosimilar – Anti-VEGF & PD1 mAb – Research Grade

Target: VEGF & PD1
Target Alias Name: Ivonescimab/AK 112/ AK-112/ AK112/VEGF & PD1/anti-VEGF & PD1
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa-[scFv]2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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