Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

21-30 of 34 results

Catalogue Number:

SH1177-F3-hFc

Category:

A

Recombinant monoclonal anti-CRP antibody
Applications: ELISA, Western Blot, Other
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: CRP (human)
Target Alias Name: 'P02741'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

TOB5-D4-hFc

Category:

A

Recombinant monoclonal anti-CRP antibody
Applications: ELISA, Western Blot, Other
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: CRP (human)
Target Alias Name: 'P02741'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

SH1579-B7-hFc

Category:

A

Recombinant monoclonal anti-FliD (Pseudomonas aeruginosa) antibody
1

Reference available

Applications: ELISA, Western Blot
Type: Primary Recombinant
Species Reactivity: Other
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: FliD (Pseudomonas aeruginosa)
Target Alias Name: 'Q9K3C5 '
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

A2-hFc

Category:

A

Recombinant monoclonal anti-gp41 (HIV) antibody
1

Reference available

Applications: ELISA, Immunoprecipitation
Type: Primary Recombinant
Species Reactivity: Other
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: gp41 (HIV)
Target Alias Name: 'ADA.C1 gp140'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

PHK121-H2-hFc

Category:

A

Recombinant monoclonal anti-LPS (Legionella pneumophila) antibody
1

Reference available

Applications: ELISA, Western Blot, Other
Type: Primary Recombinant
Species Reactivity: Other
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: LPS (Legionella pneumophila)
Target Alias Name: '-'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

PAS4-G7-hFc

Category:

A

Recombinant monoclonal anti-SMAD2 antibody
1

Reference available

Applications: ELISA, Immunocytochemistry
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: SMAD2 (human)
Target Alias Name: 'Q15796'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

SH544-IIC4-hFc

Category:

A

Recombinant monoclonal anti-SMAD3P antibody
1

Reference available

Applications: ELISA, Immunocytochemistry
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: SMAD3-P (human)
Target Alias Name: 'P84022'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

PAS7-C7-hFc

Category:

A

Recombinant monoclonal anti-SMAD4 antibody
1

Reference available

Applications: ELISA, Immunocytochemistry, Western Blot
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: SMAD4 (human)
Target Alias Name: 'Q13485'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

SH585-IIC4-hFc

Category:

A

Recombinant monoclonal anti-SMAD7 antibody
1

Reference available

Applications: ELISA, Immunocytochemistry
Type: Primary Recombinant
Species Reactivity: Human
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: SMAD7 (human)
Target Alias Name: 'O15105'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

SH1429-B1-hFc

Category:

A

Recombinant monoclonal anti-TcdB (Clostridioides difficile extoxin)
1

Reference available

Applications: ELISA, Western Blot
Type: Primary Recombinant
Species Reactivity: Other
Formulation: Sodium-azide free, BSA-free, Carrier-free, Glycerol-free, Other
Target: TcdB (Clostridioides difficile extoxin)
Target Alias Name: 'Q189K3'
Isotype/Mimetic: scFv-hFc (IgG1-Fc)
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available Yes
Original Discovery Method human-derived phage display
Original Discovery Information Provided On Datasheet Yes
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression