Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

2641-2650 of 4090 results

Catalogue Number:

PX-TA1942

Category:

G

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Duvakitug Biosimilar – Anti-TNFSF15 mAb – Research Grade

Target: TNFSF15
Target Alias Name: anti-TNFSF15/ Vascular endothelial cell growth inhibitor/ VEGI/ TL1/ TNF ligand-related molecule 1/ Tumor necrosis factor ligand superfamily member 15
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1432

Category:

G

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Duvortuxizumab Biosimilar – Anti-CD19/ CD3E mAb – Research Grade

Target: CD19/ CD3E
Target Alias Name: Duvortuxizumab/JNJ-64052781/MGD011/RES192M1.2/CD19/ CD3E/anti-CD19/ CD3E
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: scFv -h-CH2-CH3(_scFv)_h-CH2-CH3
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1903

Category:

G

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e omega DT/Diphtheria toxin Antibody (DTD4) Biosimilar – Anti-Diphtheria toxin mAb – Research Grade

Target: Diphtheria toxin
Target Alias Name: anti-Diphtheria toxin/DT/DTD/Diphtheria toxoid/
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1660

Category:

G

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Ebdarokimab Biosimilar – Anti-IL12B mAb – Research Grade

Target: IL12B
Target Alias Name: Ebdarokimab/AK-101/ EBDAROKIMAB/ EBDAROKIMAB/ IMMUNOGLOBULIN G1/ ANTI-(HUMAN INTERLEUKIN 12 SUBUNIT .BETA.) (HUMAN MONOCLONAL AK101 .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL AK101 .KAPPA.-CHAIN/ DIMER/IL12B/anti-IL12B
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1792

Category:

G

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Eblasakimab Biosimilar – Anti-IL13R mAb – Research Grade

Target: IL13R
Target Alias Name: Eblasakimab/ASLAN-004/ ASLAN004/ CSL-334/IL13R/anti-IL13R
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1661

Category:

G

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Ebronucimab Biosimilar – Anti-PCSK9 mAb – Research Grade

Target: PCSK9
Target Alias Name: Ebronucimab/EBRONUCIMAB/ IMMUNOGLOBULIN G1/ ANTI-(HUMAN NEURAL APOPTOSIS-REGULATED CONVERTASE 1) (HUMAN MONOCLONAL AK102 .GAMMA.1-CHAIN)/ DISULFIDE WITH HUMAN MONOCLONAL AK102 .LAMBDA.-CHAIN/ DIMER IMMUNOGLOBULIN G1-LAMBDA2/ ANTI-(HOMO SAPIENS PCSK9 (PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9/ NEURAL APOPTOSIS-REGULATED CONVERTASE 1/ NARC1/ NARC-1/ PROPROTEIN CONVERTASE 9/ PC9))/ HOMO SAPIENS MONOCLONAL ANTIBODY/PCSK9/anti-PCSK10
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1/Lambda
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1931

Category:

G

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EC15 Antibody (5G12) Biosimilar – Anti-CD33L3 mAb – Research Grade

Target: CD33L3
Target Alias Name: anti-CD33L3/ Siglec-15/ Sialic acid-binding Ig-like lectin 15/ SIGLEC15/ CD33 antigen-like 3/
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1 silence
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1783

Category:

G

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Ecleralimab Biosimilar – Anti-TSLP mAb – Research Grade

Target: TSLP
Target Alias Name: Ecleralimab/CSJ 117/ CSJ-117/ NVP-CSJ117/TSLP/anti-TSLP
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: Fab-G1-lambda2
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1195

Category:

G

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Ecromeximab Biosimilar – Anti-ganglioside GD4 mAb – Research Grade

Target: ganglioside GD4
Target Alias Name: Ecromeximab/KM871/KW-2871/ganglioside GD4/anti-ganglioside GD4
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG1-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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Catalogue Number:

PX-TA1039

Category:

G

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Eculizumab Biosimilar – Anti-C5 mAb – Research Grade

Target: C5
Target Alias Name: Eculizumab/5G1.1/h5G1.1HuG2/G4/C5/anti-C5
Species Reactivity: Human
Type: Primary Recombinant
Isotype/Mimetic: IgG2-G4-kappa
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Unknown
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Unknown discovery source/method, In vitro recombinant expression
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