Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

2471-2480 of 3093 results

Catalogue Number:

AP1393

Category:

Phospho-KAP1/TRIM28-S824 Rabbit mAb

Target:	TRIM28
Target Alias Names:	KAP1, TF1B, RNF96, TIF1B, PPP1R157, TIF1beta, Phospho-KAP1/TRIM28-S824
Species Reactivity:	Human, Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1517

Category:

phospho-LATS1-T1079+LATS2-T1041 Rabbit mAb

References available

Target:	LATS1/LATS2
Target Alias Names:	LATS1, WARTS, wts, phospho-LATS1-T1079+LATS2-T1041
Species Reactivity:	Human, Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), ?pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1154

Category:

Phospho-LRRK2-S935 Rabbit mAb

Target:	LRRK2
Target Alias Names:	PARK8, RIPK7, ROCO2, AURA17, DARDARIN, Phospho-LRRK2-S935
Species Reactivity:	Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1050

Category:

Phospho-Lyn-Y397 Rabbit mAb

References available

Target:	LYN
Target Alias Names:	JTK8, p53Lyn, p56Lyn, Phospho-Lyn-Y396
Species Reactivity:	Mouse
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1491

Category:

Phospho-MAP2K4-S257 Rabbit mAb

Target:	MAP2K4
Target Alias Names:	JNKK, MEK4, MKK4, SEK1, SKK1, JNKK1, SERK1, MAPKK4, PRKMK4, SAPKK1, SAPKK-1
Species Reactivity:	Human, Mouse, Rat
Applications:	Immunofluorescence, Immunoprecipitation, Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1308

Category:

Phospho-MDM2-S166 Rabbit mAb

Target:	MDM2
Target Alias Names:	HDMX, LSKB, hdm2, ACTFS, Phospho-MDM2-S166
Species Reactivity:	Human, Mouse, Rat
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1020

Category:

Phospho-MEK1-S298 Rabbit mAb

Target:	MAP2K1
Target Alias Names:	MEL, Phospho-MEK1-S298
Species Reactivity:	Human, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1021

Category:

Phospho-MEK1-T292 Rabbit mAb

References available

Target:	MAP2K1
Target Alias Names:	MEL, CFC3, MEK1, MKK1, MAPKK1, PRKMK1, Phospho-MEK1-T292
Species Reactivity:	Human, Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1349

Category:

Phospho-MEK1/MEK2-S217/S221 Rabbit mAb

References available

Target:	MAP2K1/MAP2K2
Target Alias Names:	MEK1/MEK2, Phospho-MEK1/MEK2-S217/S221
Species Reactivity:	Human, Mouse, Rat
Applications:	Immunoprecipitation, Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Catalogue Number:

AP1339

Category:

Phospho-Met-Y1234/Y1235 Rabbit mAb

Reference available

Target:	MET
Target Alias Names:	DA11, HGFR, AUTS9, RCCP2, c-Met, DFNB97, Phospho-Met-Y1234/Y1235
Species Reactivity:	Human, Mouse, Rat
Application:	Western Blot
Type:	Secondary Recombinant
Isotype/Mimetic:	IgG
Host Species:	Rabbit
Formulation:	PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Animal-Derived Biomaterials Used:	BSA
Sequence Available	No
Original Discovery Method	Immunisation post 2020 (on-going during disocvery but recombinant expression downstream)
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation

Viewing 2471-2480 of 3093 results

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