Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

2421-2430 of 4090 results

Catalogue Number:

RGK24301-100

Category:

Anti-Z-DNA Antibody (Z44)

Target:	DNA/ Z-DNA
Species Reactivity:	Other
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

RVV03601-100

Category:

Anti-Zaire ebolavirus/ZEBOV GP/GP1/2 Nanobody (SAA1248)

Target:	GP/GP1/2
Target Alias Name:	anti-Envelope glycoprotein/ anti-GP1/2/ anti-GP/ anti-Shed GP/ anti-GP1/2-delta/ anti-GP1/ anti-GP2/ anti-GP/ anti-Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus)
Species Reactivity:	Other
Type:	Primary Recombinant
Isotype/Mimetic:	VHH-8His-Cys-tag
Host Species:	Other
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1623

Category:

Anti-Zika Virus Envelope Protein Biosimilar – Anti-Zika Virus mAb – Research Grade

Target:	Zika Virus Envelope Protein Biosimilar - Anti-Zika Virus
Target Alias Name:	Anti-Zika Virus Envelope Protein/0/Zika Virus Envelope Protein Biosimilar - Anti-Zika Virus/anti-Zika Virus Envelope Protein Biosimilar - Anti-Zika Virus
Species Reactivity:	Human
Type:	Primary Recombinant
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1776

Category:

Anumigilimab Biosimilar – Anti-G-CSF receptor mAb – Research Grade

Target:	G-CSF receptor
Target Alias Name:	Anumigilimab/CSL 324/ CSL-324/ CSL324/ G-CSFR/G-CSF receptor/anti-G-CSF receptor
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2043

Category:

Anvatabart Biosimilar – Anti-HER2 mAb – Research Grade

Target:	HER2
Target Alias Name:	anti-HER2/ p185erbB2/ NGL/ Tyrosine kinase-type cell surface receptor HER2/ NEU/ MLN 19/ Proto-oncogene Neu/ MLN19/ ERBB2/ Proto-oncogene c-ErbB-2/ CD340/ Receptor tyrosine-protein kinase erbB-2/ Metastatic lymph node gene 19 protein
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA2044

Category:

Anzurstobart Biosimilar – Anti-BIT mAb – Research Grade

Target:	BIT
Target Alias Name:	anti-BIT/ Signal-regulatory protein alpha-1/ Brain Ig-like molecule with tyrosine-based activation motifs/ MFR/ SIRP/ Sirp-alpha-1/ Sirp-alpha-2/ PTPNS1/ SIRPA/ SHP substrate 1/ CD172 antigen-like family member A/ Sirp-alpha-3/ Inhibitory receptor SHPS-1/ Signal-regulatory protein alpha-3/ CD172a/ Tyrosine-protein phosphatase non-receptor type substrate 1/ MyD-1 antigen/ Bit/ SHPS-1/ Macrophage fusion receptor/ Signal-regulatory protein alpha-2/ SHPS1/ MYD1/ p84
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1431

Category:

Apamistamab Biosimilar – Anti-PTPRC/ CD45 mAb – Research Grade

Target:	PTPRC/ CD45
Target Alias Name:	Apamistamab/Iomab-B/PTPRC/ CD45/anti-PTPRC/ CD45
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-kappa
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1810

Category:

Apitegromab Biosimilar – Anti-pro-GDF-8 mAb – Research Grade

Target:	pro-GDF-8
Target Alias Name:	Apitegromab//pro-GDF-8/anti-pro-GDF-8
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG4 Lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1037

Category:

Apolizumab Biosimilar – Anti-HLA-DRB mAb – Research Grade

Target:	HLA-DRB
Target Alias Name:	Apolizumab/Hu1D10/HLA-DRB/anti-HLA-DRB
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-nd
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PX-TA1443

Category:

Aprutumab Biosimilar – Anti-FGFR2 mAb – Research Grade

Target:	FGFR2
Target Alias Name:	Aprutumab/BAY 1179470/FGFR2/anti-FGFR2
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG1-lambda
Host Species:	Human
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 2421-2430 of 4090 results

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