Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

2271-2280 of 6380 results

Catalogue Number:

HPAB-2824LY

Category:

A

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Human Anti-FASLG Recombinant Antibody (HPAB-2824LY)

Target: FASLG
Target Alias Names: FASLG, FASL, Fas Ligand, CD178, APTL, TNFSF6, Fas Antigen Ligand, ALPS1B
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-2825LY

Category:

A

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Human Anti-FASLG Recombinant Antibody (HPAB-2825LY)

Target: FASLG
Target Alias Names: FASLG, FASL, Fas Ligand, CD178, APTL, TNFSF6, Fas Antigen Ligand, ALPS1B
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0770YY

Category:

A

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Human Anti-FBXW7-AS1 Recombinant Antibody (HPAB-0770YY)

Target: FBXW7-AS1
Target Alias Names: DEAR, DEspR
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotypes/Mimetics: Humanized IgG4, κ
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0125-WJ

Category:

A

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Human Anti-Fc Receptor Recombinant Antibody (HPAB-0125-WJ)

Target: Fc Receptor
Target Alias Names: Fc receptor, FC-receptor, FC-receptor single domain
Species Reactivity: Human
Application: ELISA
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-1202WJ

Category:

A

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Human Anti-FCAR Recombinant Antibody (clone 14A8)

Target: FCAR
Target Alias Names: CD89, FcalphaRI, CTB-61M7.2
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-1203WJ

Category:

A

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Human Anti-FCAR Recombinant Antibody (clone 8D2)

Target: FCAR
Target Alias Names: CD89, FcalphaRI, CTB-61M7.2
Species Reactivity: Human
Applications: ELISA, Flow Cytometry
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

FAMAB-0279JF

Category:

A

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Human Anti-FCER1A Recombinant Antibody (clone CBMalpha8)

Target: FCER1A
Target Alias Names: FCE1A, FcERI
Species Reactivity: Human
Application: Immunohistochemistry
Type: Primary Recombinant
Isotype/Mimetic: Human IgG
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-1534WJ

Category:

A

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Human Anti-FCER1A Recombinant Antibody (clone CRA2)

Target: FCER1A
Target Alias Names: The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotypes/Mimetics: Human IgG1, κ
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-1535WJ

Category:

A

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Human Anti-FCER1A Recombinant Antibody (clone CRA4)

Target: FCER1A
Target Alias Names: The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.
Species Reactivity: Human
Applications: ELISA, Western Blot
Type: Primary Recombinant
Isotypes/Mimetics: Human IgG1, κ
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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Catalogue Number:

HPAB-0531-YJ

Category:

A

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Human Anti-FCER2 Recombinant Antibody (clone ch1E9)

Target: FCER2
Target Alias Names: CD23, FCE2, CD23A, IGEBF, CLEC4J, BLAST-2, low affinity immunoglobulin epsilon Fc receptor, C-type lectin domain family 4, member J, CD23 antigen, Fc epsilon receptor II, Fc fragment of IgE, low affinity II, receptor for (CD23), fc-epsilon-RII, immunoglobulin E-binding factor, immunoglobulin epsilon-chain, lymphocyte IgE receptor
Species Reactivity: Human
Applications: ELISA, Immunohistochemistry
Type: Primary Recombinant
Isotype/Mimetic: Chimeric (mouse/human) IgG1
Host Species: Human
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Human-derived phage display
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression
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