Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

2161-2170 of 4090 results

Catalogue Number:

RHF75501-100

Category:

Anti-Phospho-Smad3 (pT179) Antibody (1A1)

Target:	Mad3/ JV15-2/ Mothers against decapentaplegic homolog 3/ SMAD family member 3/ Smad3/ SMAD3/ MADH3/ hMAD-3/ SMAD 3/ MAD homolog 3/ hSMAD3/ Mothers against DPP homolog 3
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19240-100

Category:

Anti-Phospho-STAT3 (pY705) Monoclonal Antibody/ SAA0302

Target:	Signal transducer and activator of transcription 3/ APRF/ STAT3/ Acute-phase response factor
Species Reactivity:	Other
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19227-100

Category:

Anti-Phospho-Tau (pS396/pS404) Monoclonal Antibody/ SAA0294

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19228-100

Category:

Anti-Phospho-Tau (pS396/pS404) Monoclonal Antibody/ SAA0295

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19230-100

Category:

Anti-Phospho-Tau (pS422) Monoclonal Antibody/ SAA0296

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19229-100

Category:

Anti-Phospho-Tau (pS713) Monoclonal Antibody/ C5.2

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19225-100

Category:

Anti-Phospho-Tau (pT212/pS214) Monoclonal Antibody/ SAA0292

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19226-100

Category:

Anti-Phospho-Tau (pT212/pS214) Monoclonal Antibody/ SAA0293

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19223-100

Category:

Anti-Phospho-Tau (pT231/pS235) Monoclonal Antibody/ SAA0290

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Catalogue Number:

PTX19224-100

Category:

Anti-Phospho-Tau (pT231/pS235) Monoclonal Antibody/ SAA0291

Target:	MAPTL/ Paired helical filament-tau/ MTBT1/ Microtubule-associated protein tau/ TAU/ Neurofibrillary tangle protein/ MAPT/ PHF-tau
Species Reactivity:	Human
Type:	Primary Recombinant
Isotype/Mimetic:	IgG2a/ kappa
Host Species:	Mouse
Animal-Derived Biomaterials Used:	None
Sequence Available	No
Original Discovery Method	Unknown
Original Discovery Information Provided On Datasheet	No
Antibody/Binder Origins:	Unknown discovery source/method, In vitro recombinant expression

Viewing 2161-2170 of 4090 results

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