Antibody Category
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Applications
Antibody Types
Host Species
Species Reactivity
  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
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  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
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  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
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  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
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  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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Anti-Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3) Ankyron


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Anti-Eukaryotic peptide chain release factor GTP-binding subunit (EC 3.6.5.-) (ERF-3) (ERF3) (ERF2) (G1 to S phase transition protein 1) (Omnipotent suppressor protein 2) (PSI no more protein 2) (Polypeptide release factor 3) (Translation release factor 3) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exopolygalacturonase (EC 3.2.1.67) (Pollen allergen Pla a 2) (allergen Pla a 2.0101) Ankyron


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Anti-Exotoxin A (ETA) (EC 2.4.2.36) (NAD(+)–diphthamide ADP-ribosyltransferase) (Pseudomonas exotoxin) (PE) Ankyron


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Anti-Exotoxin A (ETA) (EC 2.4.2.36) (NAD(+)–diphthamide ADP-ribosyltransferase) (Pseudomonas exotoxin) (PE) Ankyron


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