Database | Recombinant Antibodies And Mimetics Database

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Category A

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category B

Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation

Category C

Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category D

Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation

Category E

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Category F

Original source/host: Animal
Discovery method: immunisation-based selection post 2020
Production: Recombinant expression with animal-derived biomaterials used in production or final formulation

Category G

Original source/host: Unknown
Discovery method: Unknown
Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation

Uncategorised Antibodies

Uncategorised Antibodies have Antibody/Binder Origins set in such a way as to prevent them from being assigned to a valid Antibody Category.

Click here to view all Antibody Category descriptions and to search directly by Antibody Category

Category A
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category B
- Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
- Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
- Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
Search
Category C
- Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
- Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category D
- Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
- Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
- Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
Search
Category E
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search
Category F
- Original source/host: Animal
- Discovery method: immunisation-based selection post 2020
- Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
Search
Category G
- Original source/host: Unknown
- Discovery method: Unknown
- Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
Search

1-10 of 27 results

Catalogue Number:

HCA335

Category:

HUMAN ANTI ABATACEPT

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugates:	HRP, Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ABATACEPT
Target Alias Name:	Orencia
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA336

Category:

HUMAN ANTI ABATACEPT

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugate:	Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ABATACEPT
Target Alias Name:	Orencia
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA202

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugates:	Preservative Free, Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	HuCAL Fab monovalent
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA202G

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugates:	Preservative Free, Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	HuCAL Fab monovalent
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA203

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugate:	Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA203G

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugate:	Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA205

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugate:	Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA204

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugates:	HRP, Preservative Free, Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA204G

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugates:	HRP, Preservative Free, Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgG1
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

Catalogue Number:

HCA271

Category:

HUMAN ANTI ADALIMUMAB

Application:	ELISA
Type:	Primary Recombinant
Species Reactivity:	Human
Conjugate:	Purified
Formulation:	Phosphate buffered saline, 0.09% Sodium Azide (NaN3)
Target:	ADALIMUMAB
Target Alias Name:	HUMIRA
Isotype/Mimetic:	IgE
Host Species:	Human
Animal-Derived Biomaterials Used:	No
Sequence Available	No
Original Discovery Method	Phage Display from synthetic human library
Antibody/Binder Origins:	Animal-free discovery, In vitro recombinant expression

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