Antibodies under a microscope

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  • Category A

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
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  • Category B

    • Original source/host: Animal (historic hybridoma) OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    • Recombinantly reformatted hybridomas are included as they align with the May 2020 EURL ECVAM recommendation, which permits continued use of existing, sequenced, and well-characterised hybridomas to produce recombinant monoclonal antibodies in vitro, as animals are no longer directly involved
    • Naïve, non-immunised animal B cell-derived in vitro antibody display libraries align with the May 2020 EURL ECVAM recommendation to no longer authorise the development and production of antibodies through animal immunisation
    Search

  • Category C

    • Original source/host: Naïve (human-derived B cell) or synthetic, natural or consensus framework (any species, published framework sequences) antibody or mimetic
    • Discovery method: Non-immunisation based in vitro display selection of antibody or mimetic
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category D

    • Original source/host: Animal OR naïve, non-immunised animal B cell-derived in vitro antibody display library
    • Discovery method: immunisation pre-2020 OR in vitro display selection of antibodies
    • Production: Recombinant expression ; animal-derived biomaterials used in production or final formulation
    Search

  • Category E

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

  • Category F

    • Original source/host: Animal
    • Discovery method: immunisation-based selection post 2020
    • Production: Recombinant expression with animal-derived biomaterials used in production or final formulation
    Search

  • Category G

    • Original source/host: Unknown
    • Discovery method: Unknown
    • Production: Recombinant expression with no use of animal-derived biomaterials in production or final formulation
    Search

1-10 of 12 results

Catalogue Number:

Opt7CD4

Category:

A

Anti-CD4 Optimer
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: CD4
Target Alias Name: Cluster of diffrentiation 4
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt1Cort

Category:

A

Anti-Cortisol Optimer
Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human, Goat, Mouse, Rabbit, Rat, Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Cortisol
Target Alias Names: 11β, 17α, 21-trihydroxypregn-4-ene-3, 20-dione
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt2FA

Category:

A

Anti-Folic Acid Optimer
Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human, Goat, Mouse, Rabbit, Rat, Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Folic Acid
Target Alias Names: Folate, Vitamin B9, pteroylglutamic acid
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt3FFA

Category:

A

Anti-Folinic Acid Optimer
Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human, Goat, Mouse, Rabbit, Rat, Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Folinic Acid
Target Alias Names: 5-formyltetrahydrofolic acid, leucovorin, 5-formyl-5, 6, 7, 8-tetrahydrofolate, formyltetrahydrofolic acid, folate, 5-Formyl-5, 6, 7, 8-tetrahydropteroyl-L-glutamic acid, calcium folinate, vitamin B9
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt12gdPT

Category:

A

Anti-Genetically Detoxified Pertussis Toxin Optimer
Applications: Immunoprecipitation, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Genetically detoxified Pertussis toxin
Target Alias Names: gdPT, PT
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt8gp120

Category:

A

Anti-gp120 Optimer
Application: Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: gp120
Target Alias Names: Envelope glycoprotein GP120, HIV GP120
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt11Hx

Category:

A

Anti-Hemopexin Optimer
Applications: Immunoprecipitation, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Hemopexin
Target Alias Names: Haemopexin, Hpx, Hx, beta-1B-glycoprotein
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt5Imb

Category:

A

Anti-imatinib Optimer
2

References available

Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Imatinib
Target Alias Names: Imatinib mesylate, Imatinib methansulfonate, STI-571, CGP 57148, Gleevec, Glivec, 4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide, 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide, CGP 57148, Genfatinib, N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt6Irinot

Category:

A

Anti-Irinotecan/SN-38 Optimer
3

References available

Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Irinotecan/SN-38
Target Alias Names: CPT-11, irinotecan hydrochloride, irinotecan hydrochloride trihydrate, irinotecanum, CP0, Campotsar, camptothecin-11, 7-ethyl-10-hydroxycamptothecin
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression

Catalogue Number:

Opt4MTHF

Category:

A

Anti-Methyltetrahydrofolic acid Optimer
Applications: ELISA, Other
Other Application: Biosensor
Type: Primary Recombinant
Species Reactivity: Human, Goat, Mouse, Rabbit, Rat, Other
Conjugates: Biotin, Peroxidase (HRP), Fluorophores, Quenchers, Amino, Alkynes, cholesterol, peptide tags
Formulation: Supplied in dd water
Target: Methyltetrahydrofolic acid
Target Alias Names: Levomefolic acid, folate, vitamin B9, Levomefolinic acid, 5-methyltatreahydrofolate, 5methyltetrahydrolfolic acid, Levomefolinic acid, levomefolate, MTHF
Isotype/Mimetic: DNA aptamer
Host Species: Other
Animal-Derived Biomaterials Used: None
Sequence Available No
Original Discovery Method Fully synthetic library screened in vitro
Original Discovery Information Provided On Datasheet No
Antibody/Binder Origins: Animal-free discovery, In vitro recombinant expression