Description
Recombinant monoclonal antibody to PDL1. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma YDC 127.1.1. This is a bispecific anti-mouse antibody created by fusing anti-CD47 VHH domains to the C-terminus of the heavy chains) of the anti-mouse PD-L1 antibody clone YDC 127.1.1 in a mouse IgG1 D265 format. The mouse IgG1 D265 a format is an Fc-silenced format, preventing ADCC and CDC.
Target
PDL1
Target Alias Names
CD274, Programmed death-ligand 1, PD-L1, B7 Homolog 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1
Isotypes/Mimetics
Bispecific, anti-mCD47
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression