Description
Recombinant monoclonal antibody to Integrin alpha-4/beta-7. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the synthetic antibody Vedolizumab (LDP-02). This is a reformatted mouse IgG2b Fc SilentЩ antibody, based on the original mouse IgG1 format, created for improved compatibility with existing reagents, assays and techniques.
Target
Integrin alpha-4/beta-7
Target Alias Names
Integrin ?4?7, CD49D, ITGA4:ITGB7, Peyer patches-specific homing receptor LPAM-1, ITGA4, Integrin alpha-4, CD49 antigen-like family member D, Integrin alpha-IV, VLA-4 subunit alpha, ITGB7, Integrin beta-7, Gut homing receptor beta subunit, ACT-1, LDP02, MLN-02, MLN0002, MLN02, ENTYVIO
Isotype/Mimetic
IgG2b
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression