Description
Ubiquityl-Histone H3 (Lys18) (E4D7R) Rabbit mAb recognizes endogenous levels of histone H3 protein only when ubiquitinated at Lys18. The 29 kDa band may correspond to histone H3 protein ubiquitinated at both Lys18 and either Lys14 or Lys23. This antibody may also detect a poly-ubiquitinated protein of unknown origin between 80 and 200 kDa. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of human histone H3 protein in which Lys18 is mono-ubiquitylated.
Target
H3 (Lys18) ubiquitinate
Target Alias Names
H3C1, H3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery, post-2020, In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation