Description
Recombinant monoclonal antibody to TRP-1, gp75. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma TA99. This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against TRP-1 (Fab) and one arm directed against mouse CD47 (VHH).
Targets
TRP-1, gp75
Target Alias Names
Melanoma antigen gp75, 5, 6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1
Isotype/Mimetic
IgG2a mCD47 KIH bispecific
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression