Antibodies under a microscope

HC359376

Research Grade Amulirafusp Alfa

Description

The antibody is a Chimeric SIRPα fragment fused via a (G4S)2 peptide linker to the N-terminus of both heavy chains of a chimeric immunoglobulin G1-kappa anti-human CD20. targets Human CD47/MER6 & CD20/MS4A1

Target

CD47/MER6 & CD20/MS4A1

Target Alias Names

Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6, B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20

Isotype/Mimetic

SIRPα fragment fused via a (G4S)2 peptide linker to the N-terminus of both heavy chains of a chimeric immunoglobulin G1-kappa anti-human CD20.

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

Unknown

Antibody/Binder Origins

Animal-free discovery, In vitro recombinant expression