Description
Phospho-VEGF Receptor 2 (Tyr1059) (D5A6) Rabbit mAb only detects endogenous levels of VEGFR2 proteins when phosphorylated at Tyr1059. Since VEGF receptors 1, 2 and 3 share identical sequences within the epitope region, this antibody can also detect VEGF receptors 1 and 3 when phosphorylated at corresponding tyrosine residues. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1059 of human VEGF receptor 2.
Targets
VEGFR1 (Tyr1053) phosphate, VEGFR2 (Tyr1059) phosphate, VEGFR3 (Tyr1068) phosphate
Target Alias Names
FLT1, KDR, FLT4, VEGFR1, VEGFR2, VEGFR3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation