Description
Phospho-Src Family (Tyr416) (D49G4) Rabbit mAb detects endogenous levels of Src only when phosphorylated at Tyr416. The antibody may cross-react with other Src family members (Lyn, Fyn, Lck, Yes and Hck) when phosphorylated at equivalent sites. It may cross react with overexpressed phosphorylated RTKs. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr419 of human Src protein.
Targets
Yes (Tyr426) phosphate, Lyn (Tyr397) phosphate, Lck (Tyr394) phosphate, Hck (Tyr411) phosphate, Src (Tyr419) phosphate, Fyn (Tyr420) phosphate
Target Alias Names
YES1, LYN, LCK, HCK, SRC, FYN, Yes, LYN, Lck, Hck, Src, Fyn
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation