Antibodies under a microscope

13780

Phospho-Rpb1 CTD (Ser7) (E2B6W) Rabbit mAb

Description

Phospho-Rpb1 CTD (Ser7) (E2B6W) Rabbit mAb recognizes endogenous levels of Rpb1 protein only when the carboxy-terminal domain (CTD) heptapeptide repeat [Tyr1, Ser2, Pro3, Thr4, Ser5, Pro6, Ser7] is phosphorylated at Ser7. This antibody does not cross-react with Rpb1 CTD phosphorylated at Ser2 or Ser5. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser7 of human Rpb1 CTD heptapeptide repeat.

Target

POLR2A (Ser1621) phosphate

Target Alias Name

POLR2A

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

BSA

Sequence Available

Yes

Original Discovery Method

Immunization

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation