Antibodies under a microscope

67221

Phospho-Rpb1 CTD (Ser5) (D9N5I) Rabbit mAb (Biotinylated)

Description

Phospho-Rpb1 CTD (Ser5) (D9N5I) Rabbit mAb (Biotinylated) recognizes endogenous levels of Rpb1 only when the carboxy-terminal domain (CTD) heptapeptide repeat [Tyr1, Ser2, Pro3, Thr4, Ser5, Pro6, Ser7] is phosphorylated at Ser5. This antibody does not cross-react with Rpb1 CTD phosphorylated at Ser5 or Ser7. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser2 of the human Rpb1 CTD heptapeptide repeat.

Target

POLR2A (Ser1619) phosphate

Target Alias Name

POLR2A

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

BSA

Sequence Available

Yes

Original Discovery Method

Immunization

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation