Description
Phospho-p38 MAP Kinase (Thr180/Tyr182) (12F8) Rabbit mAb detects endogenous levels of p38 MAPK only when dually phosphorylated at threonine 180 and tyrosine182. It will also react with p38 singly phosphorlyated at Thr180. This antibody does not cross-react with the phosphorylated forms of either p42/44 MAPK or SAPK/JNK. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr180/Tyr182 of human p38 MAPK.
Targets
p38-alpha MAPK (Thr180/Tyr182) phosphate, p38-delta MAPK (Thr180/Tyr182) phosphate, p38-gamma MAPK (Thr183/Tyr185) phosphate, p38-beta MAPK (Thr180/Tyr182) phosphate
Target Alias Names
MAPK14, MAPK13, MAPK12, MAPK11, P38A, P38D, P38G, P38B
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation