Description
Phospho-IGF-I Receptor β (Tyr1131)/Insulin Receptor β (Tyr1146) (D6D5L) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of IGF-I receptor β protein only when phosphorylated at Tyr1131 and/or insulin receptor β protein only when phosphorylated at Tyr1146. The antibody cross-reacts with activated ErbB2 and ALK. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Tyr1131 of human IGF-I receptor protein.
Target
IGF1R (Tyr1161) phosphate
Target Alias Name
IGF1R
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression