Description
Phospho-Histone H3 (Ser10) (D7N8E) XP® Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of histone H3 protein only when phosphorylated at Ser10. This antibody detects phosphorylation at Ser10 in the presence of acetylated or methylated Lys9, but not in the presence of phosphorylated Thr11. This antibody does not cross-react with histone H3 phosphorylated at Ser28. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding phosphorylated Ser10 of human histone H3 protein.
Target
H3 (Ser10) phosphate
Target Alias Names
H3C1, H3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression