Description
Phospho-HER3/ErbB3 (Tyr1289) (21D3) Rabbit mAb (BSA and Azide Free) detects endogenous HER3/ErbB3 proteins only when phosphorylated at tyrosine 1289. This antibody cross-reacts with overexpressed EGFR. This antibody may cross-react with overexpressed receptor tyrosine kinases in IHC. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1289 of human HER3/ErbB3.
Target
HER3/ErbB3 (Tyr1289) phosphate
Target Alias Names
ERBB3, HER3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression