Antibodies under a microscope

52928

Phospho-FGF Receptor 1 (Tyr653/654) (D4X3D) Rabbit mAb

Description

Phospho-FGF Receptor 1 (Tyr653/654) (D4X3D) Rabbit mAb recognizes endogenous levels of FGFR1 protein when phosphorylated at Tyr653 and/or Tyr654. This antibody exhibits some cross-reactivity with FGF Receptors 2 and 4 when overexpressed exogenously. Based on sequence comparisons, cross-reactivity with FGF Receptor 3 is possible but has not been experimentally confirmed. Monoclonal antibody is produced by immunizing animals with a synthetic phospho-peptide corresponding to residues surrounding Tyr653 of human FGFR1 protein.

Target

FGFR1 (Tyr653/Tyr654) phosphate

Target Alias Name

FGFR1

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

BSA

Sequence Available

Yes

Original Discovery Method

Immunization

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation