Description
Phospho-ALK (Tyr1078) (D28B4) Rabbit mAb recognizes endogenous levels of ALK only when phosphorylated at Tyr1078, which is equivalent to Tyr138 of NPM-ALK. This antibody may cross-react weakly with other overexpressed phospho-tyrosine kinases such as EGFR and Src. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1078 of human ALK protein.
Target
ALK (Tyr1078) phosphate
Target Alias Name
ALK
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation