Description
Pan-Keratin (C11) Mouse mAb (Alexa Fluor® 647 Conjugate) detects endogenous levels of total keratins 4, 5, 6, 8, 10, 13 and 18. The antibody does not cross-react with other keratins. Monoclonal antibody is produced by immunizing animals with a cytoskeleton preparation from A-431 cells. This antibody was conjugated to Alexa Fluor® 647 under optimal conditions with an F/P ratio of 2-6. The Alexa Fluor® 647 dye is maximally excited by red light (e.g. 633 nm He-Ne laser). Antibody conjugates of the Alexa Fluor® 647 dye produce bright far-red-fluorescence emission, with a peak at 665 nm.
Targets
K6c, K10, KRT6B, K8, K13, K6a, KRT18, K5, K4
Target Alias Names
KRT6C, KRT10, KRT6B, KRT8, KRT13, KRT6A, KRT18, KRT5, KRT4, K6c, K10, KRT6B, K8, K13, K6a, K18, K5, K4
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation