Antibodies under a microscope

Ab00449-1.1

M200 (Volociximab)

Description

Recombinant monoclonal antibody to alpha 5 beta 1 Integrin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma M200 (Volociximab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

Target

alpha 5 beta 1 Integrin

Target Alias Names

Fibronectin receptor, CD49 antigen-like family member E, Integrin alpha-F, VLA-5, CD49e.

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression